MYLK2 Substrate (L-A): sc-3044

The MYLK2 Substrate (L-A) is a research chemical specifically designed to study the activity of myosin light chain kinase 2 (MYLK2), an enzyme that plays a pivotal role in muscle contraction and cellular motility. This substrate is employed in biochemical assays to measure MYLK2 activity, providing insights into its function and regulation in muscle and non-muscle cells. Scientists use MYLK2 Substrate (L-A) to investigate how phosphorylation by MYLK2 alters the behavior of target proteins, particularly those involved in cytoskeletal reorganization and cellular force generation. By enabling the quantitative assessment of kinase activity, this substrate aids in exploring the molecular mechanisms underlying cellular responses to mechanical stress and signaling pathways that govern muscle contraction and cell motility. The application of MYLK2 Substrate (L-A) extends to studies on the regulation of MYLK2 itself, including its activation by calcium/calmodulin and its role in diverse cellular processes, such as smooth muscle contraction and the migration of non-muscle cells. These research applications are crucial for advancing our understanding of cellular dynamics and the molecular basis of muscle function and movement.