Date published: 2025-12-16

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MYLK/MYLK2 Substrate

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Alternate Names:
Myosin light chain kinase substrate; KKRAARATSNVFA
Application:
MYLK/MYLK2 Substrate is a synthetic substrate for MLCK
Purity:
>97% pure by HPLC
Molecular Weight:
1418.7
Molecular Formula:
C61H107N23O16
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

MYLK/MYLK2 Substrate (PG-AA) is a biologically active peptide.


MYLK/MYLK2 Substrate References

  1. The archaeon Sulfolobus solfataricus contains a membrane-associated protein kinase activity that preferentially phosphorylates threonine residues in vitro.  |  Lower, BH., et al. 2000. J Bacteriol. 182: 3452-9. PMID: 10852877
  2. Myosin light chain kinase mediates eosinophil chemotaxis in a mitogen-activated protein kinase-dependent manner.  |  Adachi, T., et al. 2003. J Allergy Clin Immunol. 111: 113-6. PMID: 12532105
  3. Inhibition of wheat embryo calcium-dependent protein kinase and other kinases by mangostin and gamma-mangostin.  |  Jinsart, W., et al. 1992. Phytochemistry. 31: 3711-3. PMID: 1368866
  4. Specificity of a Vibrio vulnificus aminopeptidase toward kinins and other peptidyl substrates.  |  Richards, GP. and Nuñez, A. 2006. J Bacteriol. 188: 2056-62. PMID: 16513735
  5. Inhibition of wheat embryo calcium-dependent protein kinase and avian myosin light chain kinase by flavonoids and related compounds.  |  Jinsart, W., et al. 1991. Biol Chem Hoppe Seyler. 372: 819-27. PMID: 1772594
  6. Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinase.  |  Kast, R., et al. 2007. Br J Pharmacol. 152: 1070-80. PMID: 17934515
  7. Activation mechanism of rabbit skeletal muscle myosin light chain kinase. 5'-p-fluorosulfonylbenzoyl adenosine as a probe of the MgATP-binding site of the calmodulin-bound and calmodulin-free enzyme.  |  Kennelly, PJ., et al. 1991. FEBS Lett. 286: 217-20. PMID: 1864371
  8. Acidic residues comprise part of the myosin light chain-binding site on skeletal muscle myosin light chain kinase.  |  Herring, BP., et al. 1990. J Biol Chem. 265: 16588-91. PMID: 2398065
  9. Spatial requirements for location of basic residues in peptide substrates for smooth muscle myosin light chain kinase.  |  Kemp, BE. and Pearson, RB. 1985. J Biol Chem. 260: 3355-9. PMID: 3838312
  10. Substrate specificity of a multifunctional calmodulin-dependent protein kinase.  |  Pearson, RB., et al. 1985. J Biol Chem. 260: 14471-6. PMID: 4055784
  11. Purification and sequencing of radish seed calmodulin antagonists phosphorylated by calcium-dependent protein kinase.  |  Polya, GM., et al. 1993. Plant Physiol. 101: 545-51. PMID: 8278508
  12. Purification and sequencing of multiple forms of Brassica napus seed napin small chains that are calmodulin antagonists and substrates for plant calcium-dependent protein kinase.  |  Neumann, GM., et al. 1996. Biochim Biophys Acta. 1295: 23-33. PMID: 8679670
  13. Demonstration of a Ca2+/calmodulin dependent protein kinase cascade in the hog heart.  |  Uemura, A., et al. 1998. Biochem Biophys Res Commun. 249: 355-60. PMID: 9712700
  14. Inhibition of eukaryote protein kinases and of a cyclic nucleotide-binding phosphatase by prenylated xanthones.  |  Lu, ZX., et al. 1998. Chem Biol Interact. 114: 121-40. PMID: 9744560

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

MYLK/MYLK2 Substrate, 1 mg

sc-3043
1 mg
$95.00