Myelin basic protein (4-14), N-acetylated (CAS 126768-94-3 (non-acetylated))
Application:
Myelin basic protein (4-14), N-acetylated is a specific substrate for α, β, γ isoforms of PKC
CAS Number:
126768-94-3 (non-acetylated)
Molecular Weight:
1432.8
Molecular Formula:
C62H105N21O18
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Myelin basic protein (4-14), N-acetylated is a section of the myelin basic protein surrounding Ser(8), residues 4-14, that is a specific substrate of PKC alpha, PKC beta, and PKC gamma, and is a poor substrate for PKA, CaMKII, CKI, CKII, and phosphorylase kinase. This sequence, Ac-QKRPSQRSKYL, is resistant to phosphatases in brain hippocampal extracts and therefore is a good substrate for use in crude extracts.
Myelin basic protein (4-14), N-acetylated (CAS 126768-94-3 (non-acetylated)) References
- Protein kinase C regulation of rat jejunal transport systems: mechanisms involved in bicarbonate absorption. | Orsenigo, MN., et al. 2002. Exp Physiol. 87: 299-309. PMID: 12089597
- A synthetic peptide substrate for selective assay of protein kinase C. | Yasuda, I., et al. 1990. Biochem Biophys Res Commun. 166: 1220-7. PMID: 1689574
- A phosphatase resistant substrate for the assay of protein kinase C in crude tissue extracts. | Farrar, YJ., et al. 1991. Biochem Biophys Res Commun. 180: 694-701. PMID: 1719969
- The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C. | Yao, L., et al. 1994. Proc Natl Acad Sci U S A. 91: 9175-9. PMID: 7522330
- Parathyroid hormone stimulation of calcium transport is mediated by dual signaling mechanisms involving protein kinase A and protein kinase C. | Friedman, PA., et al. 1996. Endocrinology. 137: 13-20. PMID: 8536604
Substrate of:
PKC α, and PKC β.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Myelin basic protein (4-14), N-acetylated, 1 mg | sc-201155 | 1 mg | $262.00 |