Myelin basic protein (4-14), N-acetylated CAS: 126768-94-3 non-acetylated
MF: C62H105N21O18
MW: 1432.8
A specific substrate for α, β, γ isoforms of PKC.

Myelin basic protein (4-14), N-acetylated (CAS 126768-94-3 non-acetylated)

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Application: Myelin basic protein (4-14), N-acetylated is a specific substrate for α, β, γ isoforms of PKC
CAS Number: 126768-94-3 non-acetylated
Molecular Weight: 1432.8
Molecular Formula: C62H105N21O18
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Myelin basic protein (4-14), N-acetylated is a section of the myelin basic protein surrounding Ser(8), residues 4-14, that is a specific substrate of PKC α, PKC β, and PKC γ, and is a poor substrate for PKA, CaMKII, CKI, CKII, and phosphorylase kinase. This sequence, Ac-QKRPSQRSKYL, is resistant to phosphatases in brain hippocampal extracts and therefore is a good substrate for use in crude extracts.


References

1. Yasuda, I., et al. 1990. Biochem. Biophys. Res. Commun. 166: 1220-1227. PMID: 1689574
2. Farrar, Y.J., et al. 1991. Biochem. Biophys. Res. Commun. 180: 694-701. PMID: 1719969

Physical State :
Solid
Sequence :
N-Acetyl-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu
Solubility :
Soluble in water
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
MDL Number :
MFCD00133371 (non-acetylated)

Download SDS (MSDS)

Certificate of Analysis

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