Mv 1 Lu Cell Lysate: sc-3810

Mv 1 Lu cell lysate is derived from the Mv 1 Lu cell line, originally isolated from mink lung epithelial cells. This lysate is extensively utilized in research to study epithelial cell biology, particularly the mechanisms of cellular adhesion, migration, and signal transduction. Mv 1 Lu cells are known for their responsiveness to transforming growth factor-beta (TGF-β), making them an ideal model for investigating TGF-β signaling pathways and their role in epithelial-mesenchymal transition (EMT). Researchers employ Mv 1 Lu cell lysate to analyze key signaling pathways such as the TGF-β/Smad, MAPK/ERK, and PI3K/Akt pathways, which are critical for regulating cell growth, differentiation, and survival. This lysate facilitates the study of protein expression, post-translational modifications, and interactions between signaling molecules that drive these pathways. Additionally, it is used to examine the effects of various chemical modulators on these signaling pathways, providing insights into the regulatory mechanisms of epithelial cell behavior and response to external stimuli. Recent studies have leveraged Mv 1 Lu cell lysate for proteomic and transcriptomic analyses to identify novel proteins and signaling networks involved in TGF-β-induced EMT and other cellular processes. By offering detailed insights into the molecular and cellular mechanisms of epithelial cells, Mv 1 Lu cell lysate remains a vital resource for advancing research in cell biology and signaling pathways.