Muscle Actin Antibody (5G2): sc-71626
- Muscle Actin Antibody (5G2) is a mouse monoclonal IgG1, cited in 3 publications, provided at 200 µg/ml
- raised against myocardium of human origin
- recommended for detection of muscle specific α and γ Actin isomers of mouse, rat and human origin by WB, IP, IF and IHC(P); non cross-reactive with beta Actin isomers
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Muscle Actin Antibody (5G2). This work is in progress.
QUICK LINKS
Muscle Actin Antibody (5G2) is a mouse monoclonal IgG2b light chain antibody that detects Muscle Actin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-Muscle Actin antibody (5G2) plays a crucial role in studying the actin cytoskeleton, which is essential for various cellular functions, including maintaining cell shape, enabling motility, and facilitating intracellular transport. Muscle Actin is a highly conserved protein that exists in multiple isoforms, being specifically associated with muscle tissue, where it forms the contractile apparatus necessary for muscle contraction. The dynamic nature of actin filaments allows rapid assembly and disassembly, which is vital for muscle function and overall cellular integrity. Additionally, Muscle Actin interacts with proteins like tropomyosin and myosin, which are critical for muscle contraction and regulation. Understanding the interactions and functions of Muscle Actin is important for elucidating mechanisms underlying muscle development and pathologies, such as muscular dystrophies. Muscle Actin (5G2) antibody serves as an invaluable tool for researchers investigating the complexities of muscle biology and actin dynamics.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Muscle Actin Antibody (5G2) References:
- Tetrahymena actin: copolymerization with skeletal muscle actin and interactions with muscle actin-binding proteins. | Hirono, M., et al. 1990. J Biochem. 107: 32-6. PMID: 2110155
- Osteopontin regulates α-smooth muscle actin and calponin in vascular smooth muscle cells. | Gao, H., et al. 2012. Cell Biol Int. 36: 155-61. PMID: 22032345
- α-smooth muscle actin is not a marker of fibrogenic cell activity in skeletal muscle fibrosis. | Zhao, W., et al. 2018. PLoS One. 13: e0191031. PMID: 29320561
- Expression of α-smooth muscle actin in the periodontal ligament during post-emergent tooth eruption. | Dorotheou, D., et al. 2018. J Int Med Res. 46: 2423-2435. PMID: 29923776
- DNA methylation regulates α-smooth muscle actin expression during cardiac fibroblast differentiation. | He, Y., et al. 2019. J Cell Physiol. 234: 7174-7185. PMID: 30362530
- MeCP2 epigenetically regulates alpha-smooth muscle actin in human lung fibroblasts. | Xiang, Z., et al. 2020. J Cell Biochem. 121: 3616-3625. PMID: 32115750
- The polymerization reaction of muscle actin. | Engel, J., et al. 1977. Mol Cell Biochem. 18: 3-13. PMID: 340937
- The role of α-smooth muscle actin in confirming the microinvasion of laryngeal squamous cell carcinoma. | Bai, Y., et al. 2021. Ann Diagn Pathol. 54: 151804. PMID: 34419855
- Comparison of Diagnostic Reliability of p63 and Smooth Muscle Actin in Salivary Gland Neoplasms. | Aswani, E., et al. 2022. Indian J Otolaryngol Head Neck Surg. 74: 2520-2526. PMID: 36452668
- Immunohistochemical localization of CD146 and alpha-smooth muscle actin during dentin formation and regeneration. | Shibui, T., et al. 2023. Anat Rec (Hoboken). 306: 2199-2207. PMID: 36627835
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Muscle Actin Antibody (5G2) | sc-71626 | 200 µg/ml | $322.00 |