Mupirocin Lithium (CAS 73346-79-9)

Mupirocin Lithium is the lithium salt of mupirocin, derived from *Pseudomonas fluorescens*, and is utilized extensively in research for its unique mechanism of action against bacterial protein synthesis. This compound specifically inhibits isoleucyl-tRNA synthetase, an essential enzyme that facilitates the incorporation of the amino acid isoleucine into bacterial proteins, effectively halting protein synthesis and thereby exerting a bacteriostatic effect. In research environments, Mupirocin Lithium is particularly valued for studying the mechanisms underlying bacterial resistance to antibiotics, as well as the genetic and enzymatic pathways involved in the biosynthesis of bioactive compounds. It serves as a pivotal model in exploring the potential for developing new antibiotic classes that mimic its targeted inhibition of tRNA synthetase. Additionally, it aids in the investigation of novel strategies to combat the rise of antibiotic-resistant bacteria, providing critical insights into the development of more effective antimicrobial agents and enhancing our understanding of microbial metabolism and genetics in a non-clinical context.