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mtp110 Antibody (2G2): sc-58807

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Datasheets
  • mtp110 Antibody (2G2) is a mouse monoclonal IgG1 κ mtp110 antibody, cited in 1 publications, provided at 200 µg/ml
  • raised against recombinant full length mtp110 of human origin
  • mtp110 Antibody (2G2) is recommended for detection of mtp110 of human origin by WB, IP, IF and ELISA
  • Anti-mtp110 Antibody (2G2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for mtp110 Antibody (2G2) for WB applications. These reagents are now offered in bundles with mtp110 Antibody (2G2) (see ordering information below).

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mtp110 Antibody (2G2) is a mouse monoclonal IgG1 kappa light chain antibody that detects the mtp110 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). mtp110 (2G2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. mtp110, a crucial mitochondrial marker located in the inner membrane of mitochondria, plays a significant role in cellular energy metabolism and is essential for oxidative phosphorylation, aiding in converting organic materials into adenosine triphosphate (ATP). This function maintains cellular energy levels, supports various cellular processes, and regulates apoptosis and cellular proliferation. Mitochondria, which house mtp110, are unique organelles that generate energy, contain their own DNA, and specific proteins serving as markers for mitochondrial studies. mtp110′s interaction with other mitochondrial proteins, such as HSP 60, during mitochondrial isolation from HeLa cells highlights its importance in understanding mitochondrial dynamics and relationships with other cellular structures. Using anti-mtp110 antibody (2G2), researchers can gain insights into mitochondrial function and its implications in various biological processes and diseases.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

mtp110 Antibody (2G2) References:

  1. New insights into transmission, diagnosis, and drug treatment of Pneumocystis carinii pneumonia.  |  Kovacs, JA., et al. 2001. JAMA. 286: 2450-60. PMID: 11712941
  2. Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases.  |  Zhu, JH., et al. 2003. Brain Pathol. 13: 473-81. PMID: 14655753
  3. Caspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signaling.  |  Sundararajan, R., et al. 2005. Oncogene. 24: 4908-20. PMID: 15824730
  4. A pool of extramitochondrial frataxin that promotes cell survival.  |  Condò, I., et al. 2006. J Biol Chem. 281: 16750-6. PMID: 16608849
  5. Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line.  |  Fiebig, AA., et al. 2006. BMC Cancer. 6: 213. PMID: 16928273
  6. Ultrastructural immunoperoxidase investigations of HCG binding to isolated testicular intertubular cells.  |  Jackson, AE. and De Kretser, DM. 1991. Histochem J. 23: 517-28. PMID: 1791159
  7. Research progress of N1-methyladenosine RNA modification in cancer.  |  Liu, Y., et al. 2024. Cell Commun Signal. 22: 79. PMID: 38291517
  8. TRMT10C gene polymorphisms confer hepatoblastoma susceptibility: evidence from a seven-center case-control study.  |  Liu, Y., et al. 2024. J Cancer. 15: 5396-5402. PMID: 39247598
  9. TRMT10C-mediated m7G modification of circFAM126A inhibits lung cancer growth by regulating cellular glycolysis.  |  Zhao, Q., et al. 2024. Cell Biol Toxicol. 40: 78. PMID: 39289194
  10. Advances in Human Pre-tRNA Maturation: TRMT10C and ELAC2 in Focus.  |  Sikarwar, J., et al. 2025. J Mol Biol. 168989. PMID: 39938738
  11. Mitochondrial glutamate dehydrogenase from Leishmania tarentolae is a guide RNA-binding protein.  |  Bringaud, F., et al. 1997. Mol Cell Biol. 17: 3915-23. PMID: 9199326
  12. The 2G2 antibody recognizes an acidic 110-kDa human mitochondrial protein.  |  Paulin-Levasseur, M., et al. 1998. Histochem J. 30: 617-25. PMID: 9870762

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

mtp110 Antibody (2G2)

sc-58807
200 µg/ml
$316.00

mtp110 Antibody (2G2): m-IgG Fc BP-HRP Bundle

sc-526915
200 µg Ab; 10 µg BP
$354.00

mtp110 Antibody (2G2): m-IgG1 BP-HRP Bundle

sc-532288
200 µg Ab; 20 µg BP
$354.00

mtp110 Antibody (2G2) AC

sc-58807 AC
500 µg/ml, 25% agarose
$416.00

mtp110 Antibody (2G2) HRP

sc-58807 HRP
200 µg/ml
$316.00

mtp110 Antibody (2G2) FITC

sc-58807 FITC
200 µg/ml
$330.00

mtp110 Antibody (2G2) PE

sc-58807 PE
200 µg/ml
$343.00

mtp110 Antibody (2G2) Alexa Fluor® 488

sc-58807 AF488
200 µg/ml
$357.00

mtp110 Antibody (2G2) Alexa Fluor® 546

sc-58807 AF546
200 µg/ml
$357.00

mtp110 Antibody (2G2) Alexa Fluor® 594

sc-58807 AF594
200 µg/ml
$357.00

mtp110 Antibody (2G2) Alexa Fluor® 647

sc-58807 AF647
200 µg/ml
$357.00

mtp110 Antibody (2G2) Alexa Fluor® 680

sc-58807 AF680
200 µg/ml
$357.00

mtp110 Antibody (2G2) Alexa Fluor® 790

sc-58807 AF790
200 µg/ml
$357.00

How much sample do you recommend loading on the gel for Western blot detection using mtp110 (2G2): sc-58807?

Asked by: Randy McDonald
We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-01
  • y_2025, m_12, d_7, h_8CST
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Rated 5 out of 5 by from Good specificity and signal strength in HeLaGood specificity and signal strength in HeLa whole cell lysate. -SCBT QC
Date published: 2014-09-26
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mtp110 Antibody (2G2) is rated 5.0 out of 5 by 1.
  • y_2025, m_12, d_7, h_8
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