MT 16 kDa antigen Antibody (HTM61): sc-52099

MT 16 kDa antigen Antibody (HTM61) is a mouse monoclonal IgG1 antibody that detects MT 16 kDa antigen protein of Mycobacterium tuberculosis origin by western blotting (WB). Anti-MT 16 kDa antigen antibody (HTM61) is available as the non-conjugated format. MT 16 kDa antigen plays a crucial role in the immune response to Mycobacterium tuberculosis, as MT 16 kDa antigen is known to elicit specific immune reactions in infected individuals, making MT 16 kDa antigen a valuable target for diagnostic and therapeutic applications. MT 16 kDa antigen is primarily located in the cytoplasm of the bacteria, where MT 16 kDa antigen is involved in the stress response and helps the pathogen survive within the hostile environment of the host. MT 16 kDa antigen′s ability to provoke a robust immune response is significant, as MT 16 kDa antigen aids in the development of peptide-based diagnostic reagents and subunit vaccines aimed at combating tuberculosis. Understanding MT 16 kDa antigen′s function and location is essential for researchers working on TB diagnostics and vaccine development, as MT 16 kDa antigen provides insights into how the bacterium interacts with the host immune system.

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MT 16 kDa antigen Antibody (HTM61) References:

1. Purification and characterization of three immunodominant proteins (38, 30, and 16 kDa) of Mycobacterium tuberculosis.  |  Devi, KR., et al. 2002. Protein Expr Purif. 24: 188-95. PMID: 11858712
2. Immunoglobulin G, A, and M responses in serum and circulating immune complexes elicited by the 16-kilodalton antigen of Mycobacterium tuberculosis.  |  Raja, A., et al. 2002. Clin Diagn Lab Immunol. 9: 308-12. PMID: 11874868
3. Identification of epitopes of Mycobacterium tuberculosis 16-kDa protein recognized by human leukocyte antigen-A*0201 CD8(+) T lymphocytes.  |  Caccamo, N., et al. 2002. J Infect Dis. 186: 991-8. PMID: 12232840
4. Humoral immune response against 38-kDa and 16-kDa mycobacterial antigens in bone and joint tuberculosis.  |  Demkow, U., et al. 2002. Int J Tuberc Lung Dis. 6: 1023-8. PMID: 12475150
5. Autophosphorylation of the 16 kDa and 70 kDa antigens (Hsp 16.3 and Hsp 70) of Mycobacterium tuberculosis.  |  Preneta, R., et al. 2004. Microbiology (Reading). 150: 2135-2141. PMID: 15256556
6. Epitope-specific antibody levels demonstrate recognition of new epitopes and changes in titer but not affinity during treatment of tuberculosis.  |  Bothamley, GH. 2004. Clin Diagn Lab Immunol. 11: 942-51. PMID: 15358657
7. In vitro T-cell immunogenicity of oligopeptides derived from the region 92-110 of the 16-kDa protein of Mycobacterium tuberculosis.  |  Bosze, S., et al. 2004. Biopolymers. 76: 467-76. PMID: 15386261
8. Th0 to Th1 switch of CD4 T cell clones specific from the 16-kDa antigen of Mycobacterium tuberculosis after successful therapy: lack of involvement of epitope repertoire and HLA-DR.  |  Caccamo, N., et al. 2005. Immunol Lett. 98: 253-8. PMID: 15860225
9. Antibody profiles characteristic of Mycobacterium tuberculosis infection state.  |  Davidow, A., et al. 2005. Infect Immun. 73: 6846-51. PMID: 16177363

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-MT 16 kDa antigen Antibody (HTM61) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

MT 16 kDa antigen Antibody (HTM61) Specifications

Alternate Product Name: MT 16 kDa antigen

Product Clone Name: HTM61

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: 16 kDa antigen

Epitope Species: Mycobacterium tuberculosis

Product Reactivity/Detection: the 16 kDa antigen

Species Reactivity/Detection: Mycobacterium tuberculosis

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for MT 16 kDa antigen Antibody (HTM61): N/A