Molecular structure of MRS 2690, CAS Number: 15039-58-4
MRS 2690 (CAS 15039-58-4)
Alternate Names:
Diphosphoric acid 1-α-D-glucopyranosyl ester 2-[(4′-methylthio)uridin-5′′-yl] ester disodium salt
Application:
MRS 2690 is a potent agonist of the GPR105 receptor
CAS Number:
15039-58-4
Purity:
≥98%
Molecular Weight:
626.33
Molecular Formula:
C15H22N2Na2O16P2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Potent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.
MRS 2690 (CAS 15039-58-4) References
- Development of a comprehensive set of P2 receptor pharmacological research compounds. | Felix, RA., et al. 2012. Purinergic Signal. 8: 101-12. PMID: 22052555
- Molecular Structure of P2Y Receptors: Mutagenesis, Modeling, and Chemical Probes. | Jacobson, KA., et al. 2012. Wiley Interdiscip Rev Membr Transp Signal. 1: PMID: 23336097
- The nucleotide sugar UDP-glucose mobilizes long-term repopulating primitive hematopoietic cells. | Kook, S., et al. 2013. J Clin Invest. 123: 3420-35. PMID: 23863713
- G-CSF: From granulopoietic stimulant to bone marrow stem cell mobilizing agent. | Bendall, LJ. and Bradstock, KF. 2014. Cytokine Growth Factor Rev. 25: 355-67. PMID: 25131807
- Nucleoside 5'-O-monophosphorothioates as modulators of the P2Y14 receptor and mast cell degranulation. | Gendaszewska-Darmach, E., et al. 2016. Oncotarget. 7: 69358-69370. PMID: 27732965
Activator of:
GPR105.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MRS 2690, 1 mg | sc-204104 | 1 mg | $398.00 |