Molecular structure of MRS 2179 ammonium salt, CAS Number: 101204-49-3
MRS 2179 ammonium salt (CAS 101204-49-3)
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Alternate Names:
2′-Deoxy-N6-methyl adenosine 3′,5′-diphosphate diammonium salt
Application:
MRS 2179 ammonium salt is a competitive P2Y12 (P2Y1 puinoreceptor) antagonist
CAS Number:
101204-49-3
Purity:
≥98%
Molecular Weight:
425.23 (free acid basis)
Molecular Formula:
C11H17N5O9P2•xNH3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
MRS 2179 ammonium salt is a competitive P2Y12 (P2Y1 puinoreceptor) antagonist. The P2Y1 receptor is a G protein-coupled receptor (GPCR) that responds to extracellular nucleotides, such as adenosine diphosphate (ADP), playing a role in various physiological processes including platelet aggregation. In biomedical research, MRS 2179 is utilized to investigate the function of the P2Y1 receptor in various cellular and physiological processes. By blocking this receptor, MRS 2179 helps in delineating the pathways mediated by P2Y1, offering insights into the role of purinergic signaling. Making MRS 2179 an ammonium salt hydrate increases its solubility in aqueous solutions.
MRS 2179 ammonium salt (CAS 101204-49-3) References
- Neuromedin U potentiates ADP- and epinephrine-induced human platelet activation. | Grippi, C., et al. 2017. Thromb Res. 159: 100-108. PMID: 29078099
- Massive efflux of adenosine triphosphate into the extracellular space immediately after experimental traumatic brain injury. | Moro, N., et al. 2021. Exp Ther Med. 21: 575. PMID: 33850547
- ADP receptor P2Y12 is the capstone of the cross-talk between Ca2+ mobilization pathways dependent on Ca2+ ATPases sarcoplasmic/endoplasmic reticulum type 3 and type 2b in platelets. | Feng, M., et al. 2023. Res Pract Thromb Haemost. 7: 100004. PMID: 36970741
Inhibitor of:
Gα 15, NTPDase8, P2X6, P2Y1, P2Y12, P2Y13, P2Y2, P2Y5, and RGS1.Activator of:
GPR105.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MRS 2179 ammonium salt, 5 mg | sc-253058 | 5 mg | $307.00 |