MRP-S25 Antibody (LB-L4): sc-134393

MRP-S25 Antibody (LB-L4) is a mouse monoclonal IgG2a kappa light chain antibody that detects MRP-S25 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-MRP-S25 antibody (LB-L4) is available as the non-conjugated format. MRP-S25, also known as mitochondrial ribosomal protein S25 or S25mt, is a crucial component of the mitochondrial ribosome, specifically found in the 28S subunit. This 173 amino acid protein plays a vital role in mitochondrial protein synthesis, which is essential for the proper functioning of mitochondria, the powerhouse of the cell. MRP-S25 localization within the mitochondria underscores its importance in the translation of mitochondrial mRNA, which encodes proteins necessary for oxidative phosphorylation and energy production. Given that mitochondrial dysfunction is implicated in various diseases, including neurodegenerative disorders and metabolic syndromes, studying MRP-S25 and its interactions is critical for understanding mitochondrial biology and potential therapeutic targets.

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MRP-S25 Antibody (LB-L4) References:

1. A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins.  |  Koc, EC., et al. 2000. J Biol Chem. 275: 32585-91. PMID: 10938081
2. Characterization of long cDNA clones from human adult spleen.  |  Hattori, A., et al. 2000. DNA Res. 7: 357-66. PMID: 11214971
3. The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present.  |  Cavdar Koc, E., et al. 2001. J Biol Chem. 276: 19363-74. PMID: 11279123
4. The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.  |  Kenmochi, N., et al. 2001. Genomics. 77: 65-70. PMID: 11543634
5. Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome.  |  Zhang, Z. and Gerstein, M. 2003. Genomics. 81: 468-80. PMID: 12706105

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-MRP-S25 Antibody (LB-L4) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-MRP-S25 Antibody (LB-L4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

MRP-S25 Antibody (LB-L4) Specifications

Alternate Product Name: MRP-S25

Product Clone Name: LB-L4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 1-174

Epitope Target: MRP-S25

Epitope Species: human

Product Reactivity/Detection: MRP-S25

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for MRP-S25 Antibody (LB-L4): N/A