MPPED2 Antibody (NQ-A35): sc-134391

MPPED2 Antibody (NQ-A35) is a mouse monoclonal IgM antibody that detects MPPED2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-MPPED2 antibody (NQ-A35) is available as a non-conjugated monoclonal isotype antibody. MPPED2, also known as Metallophosphoesterase domain-containing protein 2, C11orf8, FAM1B, or 239FB, is a 294 amino acid protein primarily expressed in fetal brain tissue, highlighting its potential role in neurodevelopment. MPPED2 is believed to be involved in various cellular processes, including the regulation of phosphoesterase activity, which is crucial for maintaining cellular homeostasis and signaling pathways. Understanding MPPED2 function is important as dysregulation may contribute to the development of neurological disorders. MPPED2 gene is located on chromosome 11, a region known for its dense association with various diseases, including ataxia-telangiectasia and several blood disorders. Anti-MPPED2 antibody (NQ-A35) effectively detects MPPED2 across multiple species, making this reagent a valuable tool for researchers studying its role in health and disease.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

MPPED2 Antibody (NQ-A35) References:

1. The 11q terminal deletion disorder: a prospective study of 110 cases.  |  Grossfeld, PD., et al. 2004. Am J Med Genet A. 129A: 51-61. PMID: 15266616
2. Human chromosome 11 DNA sequence and analysis including novel gene identification.  |  Taylor, TD., et al. 2006. Nature. 440: 497-500. PMID: 16554811
3. KCNQ1 K+ channel-mediated cardiac channelopathies.  |  Loussouarn, G., et al. 2006. Methods Mol Biol. 337: 167-83. PMID: 16929947
4. Skipping of Exon 1 in the KCNQ1 gene causes Jervell and Lange-Nielsen syndrome.  |  Zehelein, J., et al. 2006. J Biol Chem. 281: 35397-403. PMID: 16987820
5. Beta-thalassaemia and sickle cell anaemia as paradigms of hypercoagulability.  |  Ataga, KI., et al. 2007. Br J Haematol. 139: 3-13. PMID: 17854302
6. A WAGR region gene between PAX-6 and FSHB expressed in fetal brain.  |  Schwartz, F., et al. 1994. Hum Genet. 94: 658-64. PMID: 7527372
7. cDNA sequence, genomic organization, and evolutionary conservation of a novel gene from the WAGR region.  |  Schwartz, F., et al. 1995. Genomics. 29: 526-32. PMID: 8666403
8. The 239AB gene on chromosome 22: a novel member of an ancient gene family.  |  Schwartz, F. and Ota, T. 1997. Gene. 194: 57-62. PMID: 9266672