MOX-2 Antibody (JJ-7): sc-81971

MOX-2 Antibody (JJ-7) is a mouse monoclonal IgG1 antibody that detects MOX-2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). MOX-2, also known as mesenchyme homeobox 2 or GAX, plays a pivotal role in axial skeleton development, highlighting its importance in the proper formation of skeletal structures. While MOX-2 is not required for the migration of myogenic precursors into the limb bud, MOX-2 is essential for normal appendicular muscle formation and the regulation of myogenic genes, underscoring its critical function in muscle development. MOX-2 expression is notably present in placental tissue, and the human MEOX2 gene, which encodes MOX-2, is located on chromosome 7p21.1. Mutations in MEOX2 have been implicated in craniofacial and skeletal abnormalities, further emphasizing the significance of MOX-2 in developmental biology. Anti-MOX-2 antibody (JJ-7) is an invaluable tool for researchers studying the intricate processes of mesodermal differentiation and skeletal development.

The preferred MOX-2 antibody is MOX-2 Antibody (A-8): sc-376748.