Molecular structure of Morroniside, CAS Number: 25406-64-8
Morroniside (CAS 25406-64-8)
CAS Number:
25406-64-8
Molecular Weight:
406.38
Molecular Formula:
C17H26O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Morroniside is a naturally occurring compound sourced from the root bark of Morus alba, a species in the Moraceae family. It′s a proficient suppressor of inflammatory cytokines and has been discovered to exhibit antioxidant, anticancer, antiviral, and antibacterial activities. Moreover, morroniside has shown to have positive effects on the cardiovascular system and the central nervous system. It acts as a suppressor of inflammatory cytokines, including TNF-α, IL-1β, and IL-6. Additionally, morroniside has been discovered to curtail the expression of pro-inflammatory enzymes like cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS).
Morroniside (CAS 25406-64-8) References
- Morroniside attenuates high glucose-induced BMSC dysfunction by regulating the Glo1/AGE/RAGE axis. | Sun, Y., et al. 2020. Cell Prolif. 53: e12866. PMID: 32643284
- Morroniside suppresses hydrogen peroxide-stimulated autophagy and apoptosis in rat ovarian granulosa cells through the PI3K/AKT/mTOR pathway. | Deng, D., et al. 2021. Hum Exp Toxicol. 40: 577-586. PMID: 32954801
- Morroniside attenuates apoptosis and pyroptosis of chondrocytes and ameliorates osteoarthritic development by inhibiting NF-κB signaling. | Yu, H., et al. 2021. J Ethnopharmacol. 266: 113447. PMID: 33022338
- Morroniside promotes the osteogenesis by activating PI3K/Akt/mTOR signaling. | Liu, H., et al. 2021. Biosci Biotechnol Biochem. 85: 332-339. PMID: 33604633
- The neuroprotective role of morroniside against spinal cord injury in female rats. | Duan, FX., et al. 2021. Neurochem Int. 148: 105105. PMID: 34147513
- Effect of morroniside on the transcriptome profiles of rat in injured spinal cords. | Shi, YJ., et al. 2022. Gene. 823: 146338. PMID: 35245640
- Morroniside, a novel GATA3 binding molecule, inhibits hepatic stellate cells activation by enhancing lysosomal acid lipase expression. | An, L., et al. 2022. Phytomedicine. 103: 154199. PMID: 35679793
- Beclin1- and Atg13-dependent autophagy activation and morroniside have synergistic effect on osteoblastogenesis. | Li, X., et al. 2022. Exp Biol Med (Maywood). 247: 1764-1775. PMID: 35957534
- Morroniside Protects Human Granulosa Cells against H2O2-Induced Oxidative Damage by Regulating the Nrf2 and MAPK Signaling Pathways. | Ma, Y., et al. 2022. Evid Based Complement Alternat Med. 2022: 8099724. PMID: 36118095
- Morroniside attenuates nucleus pulposus cell senescence to alleviate intervertebral disc degeneration via inhibiting ROS-Hippo-p53 pathway. | Zhou, C., et al. 2022. Front Pharmacol. 13: 942435. PMID: 36188539
- Morroniside alleviates lipopolysaccharide-induced inflammatory and oxidative stress in inflammatory bowel disease by inhibiting NLRP3 and NF-κB signaling pathways. | Zhang, S., et al. 2022. Allergol Immunopathol (Madr). 50: 93-99. PMID: 36335451
- Morroniside Regulates Endothelial Cell Function via the EphrinB Signaling Pathway after Oxygen-Glucose Deprivation In Vitro. | Liu, T., et al. 2022. Evid Based Complement Alternat Med. 2022: 6875053. PMID: 36573084
- Morroniside ameliorates inflammatory skeletal muscle atrophy via inhibiting canonical and non-canonical NF-κB and regulating protein synthesis/degradation. | Yi, X., et al. 2022. Front Pharmacol. 13: 1056460. PMID: 36618945
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Morroniside, 1 mg | sc-483523A | 1 mg | $229.00 | |||
Morroniside, 5 mg | sc-483523B | 5 mg | $658.00 | |||
Morroniside, 10 mg | sc-483523 | 10 mg | $1107.00 |