Date published: 2025-10-14

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Montelukast-d6, Sodium Salt

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Alternate Names:
1-[1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl-d6)phenyl]propyl]thio]methyl]cyclopropaneacetic Acid Sodium Salt; MK-476-d6; Singulair
Application:
Montelukast-d6, Sodium Salt is a selective CysLT1 Receptor (leukotriene D4-receptor) antagonist
Molecular Weight:
614.20
Molecular Formula:
C35H29D6ClNNaO3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Montelukast-d6, Sodium Salt is a compound that functions as a leukotriene receptor antagonist. It acts by selectively binding to the cysteinyl leukotriene receptor CysLT1 in the airway. This interaction inhibits the physiological actions of leukotriene D4, which include bronchoconstriction, mucous secretion, vascular permeability, and eosinophil recruitment. By blocking the receptor, Montelukast-d6, Sodium Salt prevents the biological effects of leukotriene D4, ultimately leading to a reduction in inflammation and constriction of the airways. Montelukast-D6, Sodium Salt′s mechanism of action involves interfering with the signaling pathways mediated by leukotriene receptors, thereby modulating the inflammatory response in experimental models.


Montelukast-d6, Sodium Salt References

  1. Method development and validation of montelukast in human plasma by HPLC coupled with ESI-MS/MS: application to a bioequivalence study.  |  Challa, BR., et al. 2010. Sci Pharm. 78: 411-22. PMID: 21179354

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Montelukast-d6, Sodium Salt, 1 mg

sc-218876
1 mg
$331.00