Date published: 2026-4-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

Monosodium Succinate (CAS 2922-54-5)

0.0(0)
Write a reviewAsk a question

Alternate Names:
Sodium Bisuccinate; Sodium Hydrogen Succinate; Succinic Acid Monosodium Salt
CAS Number:
2922-54-5
Molecular Weight:
140.07
Molecular Formula:
C4H6NaO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Monosodium succinate, also referred to as monosodium glutamate (MSG), is a tasteless and odorless white crystalline powder employed as a flavor enhancer in various food products. It is the sodium salt derived from the amino acid glutamate and is produced through the fermentation process of sugar cane. For many years, monosodium succinate has been utilized by the food industry to enhance the taste of numerous processed and packaged foods.


Monosodium Succinate (CAS 2922-54-5) References

  1. Surface-active agents and cellular metabolism. II. Micelle formation as a factor in the inhibition of yeast metabolism by long-chain alkyl sulfates.  |  ARMSTRONG, WM. 1958. Arch Biochem Biophys. 74: 427-36. PMID: 13534671
  2. Correlation between cataract and retinopathy due to lighting in F344 rats used in a long-term carcinogenicity study.  |  Toyoda, K., et al. 1992. J Toxicol Environ Health. 37: 495-509. PMID: 1464905
  3. Instability of the protoplast membrane of facultative alkaliphilic Bacillus sp. C-125 at alkaline pH values below the pH optimum for growth.  |  Aono, R., et al. 1992. Biochem J. 285 (Pt 1): 99-103. PMID: 1637326
  4. Stabilization of protein structure in freeze-dried amorphous organic acid buffer salts.  |  Izutsu, K., et al. 2009. Chem Pharm Bull (Tokyo). 57: 1231-6. PMID: 19881273
  5. Calorimetric and diffractometric evidence for the sequential crystallization of buffer components and the consequential pH swing in frozen solutions.  |  Sundaramurthi, P., et al. 2010. J Phys Chem B. 114: 4915-23. PMID: 20302316
  6. Crystallization of trehalose in frozen solutions and its phase behavior during drying.  |  Sundaramurthi, P., et al. 2010. Pharm Res. 27: 2374-83. PMID: 20811935
  7. The effect of crystallizing and non-crystallizing cosolutes on succinate buffer crystallization and the consequent pH shift in frozen solutions.  |  Sundaramurthi, P. and Suryanarayanan, R. 2011. Pharm Res. 28: 374-85. PMID: 20927571
  8. Thermophysical properties of carboxylic and amino acid buffers at subzero temperatures: relevance to frozen state stabilization.  |  Sundaramurthi, P. and Suryanarayanan, R. 2011. J Phys Chem B. 115: 7154-64. PMID: 21561117
  9. Lack of toxicity/carcinogenicity of monosodium succinate in F344 rats.  |  Maekawa, A., et al. 1990. Food Chem Toxicol. 28: 235-41. PMID: 2358249
  10. Predicting the crystallization propensity of carboxylic acid buffers in frozen systems--relevance to freeze-drying.  |  Sundaramurthi, P. and Suryanarayanan, R. 2011. J Pharm Sci. 100: 1288-93. PMID: 24081466
  11. A novel pulsatile drug delivery system based on the physiochemical reaction between acrylic copolymer and organic acid: in vitro and in vivo evaluation.  |  Zhang, Z., et al. 2014. Int J Pharm. 462: 66-73. PMID: 24368107
  12. Mesoporous Octahedron-Shaped Tricobalt Tetroxide Nanoparticles for Photocatalytic Degradation of Toxic Dyes.  |  Sonkusare, VN., et al. 2020. ACS Omega. 5: 7823-7835. PMID: 32309692
  13. Trehalose crystallization during freeze-drying: Implications on lyoprotection  |  Sundaramurthi, P., & Suryanarayanan, R. 2010. The Journal of Physical Chemistry Letters. 1(2): 510-514.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Monosodium Succinate, 25 g

sc-474242
25 g
$52.00