Date published: 2025-11-3

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Monobenzyl Phthalate (CAS 2528-16-7)

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Alternate Names:
1,2-Benzenedicarboxylic Acid 1-(Phenylmethyl) Ester
Application:
Monobenzyl Phthalate is a phthalate metabolite
CAS Number:
2528-16-7
Molecular Weight:
256.25
Molecular Formula:
C15H12O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Monobenzyl phthalate is a plasticizer and is used to increase the flexibility and durability of various polymer materials. It acts by interacting with the polymer chains, reducing intermolecular forces and allowing the chains to slide past each other more easily. This results in improved flexibility and resistance to breakage in the final polymer product. At the molecular level, monobenzyl phthalate disrupts the packing of polymer chains, leading to a more amorphous structure and enhancing the mechanical properties of the material. Its mechanism of action involves binding to the polymer matrix and altering its physical properties, making it a useful additive in the development of various plastic and rubber products.


Monobenzyl Phthalate (CAS 2528-16-7) References

  1. Decreased anogenital distance and increased incidence of undescended testes in fetuses of rats given monobenzyl phthalate, a major metabolite of butyl benzyl phthalate.  |  Ema, M., et al. 2003. Reprod Toxicol. 17: 407-12. PMID: 12849851
  2. Temporal trends in phthalate exposures: findings from the National Health and Nutrition Examination Survey, 2001-2010.  |  Zota, AR., et al. 2014. Environ Health Perspect. 122: 235-41. PMID: 24425099
  3. Sensitive liquid chromatography-tandem mass spectrometry method for the simultaneous determination of benzyl butyl phthalate and its metabolites, monobenzyl phthalate and monobutyl phthalate, in rat plasma, urine, and various tissues collected from a toxicokinetic study.  |  Kim, MG., et al. 2015. Anal Bioanal Chem. 407: 7391-400. PMID: 26168976
  4. Characterization of Urinary Phthalate Metabolites Among Custodians.  |  Cavallari, JM., et al. 2015. Ann Occup Hyg. 59: 982-99. PMID: 26240196
  5. Phthalate Metabolites, Consumer Habits and Health Effects.  |  Wallner, P., et al. 2016. Int J Environ Res Public Health. 13: PMID: 27428989
  6. Inhibition of UDP-glucuronosyltransferases (UGTs) by phthalate monoesters.  |  Du, Z., et al. 2018. Chemosphere. 197: 7-13. PMID: 29328989
  7. The extent and predictors of phthalate exposure among couples undergoing in vitro fertilization treatment.  |  Al-Saleh, I., et al. 2019. Environ Monit Assess. 191: 316. PMID: 31041540
  8. Phthalate metabolites in harbor porpoises (Phocoena phocoena) from Norwegian coastal waters.  |  Rian, MB., et al. 2020. Environ Int. 137: 105525. PMID: 32028175
  9. Association between follicular fluid phthalate concentrations and extracellular vesicle microRNAs expression.  |  Barnett-Itzhaki, Z., et al. 2021. Hum Reprod. 36: 1590-1599. PMID: 33885134
  10. Exposure to endocrine disrupting chemicals (EDCs) and cardiometabolic indices during pregnancy: The HOME Study.  |  Vuong, AM., et al. 2021. Environ Int. 156: 106747. PMID: 34425642
  11. Phthalate monoesters act through peroxisome proliferator-activated receptors in the mouse ovary.  |  Meling, DD., et al. 2022. Reprod Toxicol. 110: 113-123. PMID: 35421560
  12. Phthalate Exposure and Oxidative/Nitrosative Stress in Childhood Asthma: A Nested Case-Control Study with Propensity Score Matching.  |  Chang, JW., et al. 2022. Biomedicines. 10: PMID: 35740459
  13. Association of Endocrine-Disrupting Chemicals with All-Cause and Cause-Specific Mortality in the U.S.: A Prospective Cohort Study.  |  Fan, Y., et al. 2023. Environ Sci Technol. 57: 2877-2886. PMID: 36728834

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Monobenzyl Phthalate, 100 mg

sc-397638
100 mg
$85.00