Date published: 2026-2-17

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Mometasone Furoate (CAS 83919-23-7)

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Application:
Mometasone Furoate is an anti-inflammatory agent
CAS Number:
83919-23-7
Purity:
≥98%
Molecular Weight:
521.44
Molecular Formula:
C27H30Cl2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Mometasone Furoate is a corticosteroid. It is a potent glucocorticoid with high affinity for the glucocorticoid receptor and low affinity for the mineralocorticoid receptor. Mometasone furoate works by inhibiting the production of inflammatory mediators and reducing the migration of inflammatory cells to the site of inflammation. It also suppresses the immune response and decreases the production of pro-inflammatory cytokines.


Mometasone Furoate (CAS 83919-23-7) References

  1. A review of the pharmacology and pharmacokinetics of inhaled fluticasone propionate and mometasone furoate.  |  Crim, C., et al. 2001. Clin Ther. 23: 1339-54. PMID: 11589253
  2. Inhaled mometasone furoate: A review of its use in persistent asthma in adults and adolescents.  |  McCormack, PL. and Plosker, GL. 2006. Drugs. 66: 1151-68. PMID: 16789800
  3. The efficacy and safety of mometasone furoate delivered via a dry powder inhaler for the treatment of asthma.  |  Meltzer, EO. and Wenzel, S. 2006. J Asthma. 43: 765-72. PMID: 17169829
  4. Mometasone furoate dry powder inhaler: a once-daily inhaled corticosteroid for the treatment of persistent asthma.  |  Karpel, JP. and Nelson, H. 2007. Curr Med Res Opin. 23: 2897-911. PMID: 17922978
  5. Inhaled mometasone furoate improves health-related quality of life in patients with persistent asthma.  |  Karpel, J., et al. 2008. J Asthma. 45: 747-53. PMID: 18972289
  6. Mometasone furoate nasal spray for the treatment of asthma.  |  Meteran, H. and Backer, V. 2016. Expert Opin Investig Drugs. 25: 999-1004. PMID: 27218300
  7. Comparative safety and efficacy of topical mometasone furoate with other topical corticosteroids.  |  Spada, F., et al. 2018. Australas J Dermatol. 59: e168-e174. PMID: 29411351
  8. Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials.  |  Gevaert, P., et al. 2020. J Allergy Clin Immunol. 146: 595-605. PMID: 32524991
  9. Mometasone furoate-loaded aspasomal gel for topical treatment of psoriasis: formulation, optimization, in vitro and in vivo performance.  |  Shinde, G., et al. 2022. J Dermatolog Treat. 33: 885-896. PMID: 32603203
  10. Fixed-dose combination of indacaterol/glycopyrronium/mometasone furoate once-daily versus salmeterol/fluticasone twice-daily plus tiotropium once-daily in patients with uncontrolled asthma: A randomised, Phase IIIb, non-inferiority study (ARGON).  |  Gessner, C., et al. 2020. Respir Med. 170: 106021. PMID: 32843164
  11. Pharmacokinetics of mometasone furoate delivered via two dry powder inhalers.  |  Vaidya, S., et al. 2021. Pulm Pharmacol Ther. 70: 102019. PMID: 33771722
  12. Mometasone furoate nasal spray in the treatment of patients with COVID-19 olfactory dysfunction: A randomized, double blind clinical trial.  |  Kasiri, H., et al. 2021. Int Immunopharmacol. 98: 107871. PMID: 34147912
  13. Inhaled indacaterol/glycopyrronium/mometasone furoate fixed-dose combination in moderate-to-severe asthma.  |  de Llano, LP., et al. 2022. Expert Rev Respir Med. 16: 1-15. PMID: 34783265
  14. A Review of the Unique Drug Development Strategy of Indacaterol Acetate/Glycopyrronium Bromide/Mometasone Furoate: A First-in-Class, Once-Daily, Single-Inhaler, Fixed-Dose Combination Treatment for Asthma.  |  Brittain, D., et al. 2022. Adv Ther. 39: 2365-2378. PMID: 35072888
  15. Intranasal corticosteroid and antihistamine combinations in the treatment of allergic rhinitis: the role of the novel formulation olopatadine/mometasone furoate.  |  Ridolo, E., et al. 2023. Expert Rev Clin Immunol. 19: 575-584. PMID: 37038974

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Mometasone Furoate, 10 mg

sc-211919
10 mg
$146.00