Molecular structure of Moguisteine, CAS Number: 119637-67-1
Moguisteine (CAS 119637-67-1)
Application:
Moguisteine is an antitussive with properties similar to codeine
CAS Number:
119637-67-1
Molecular Weight:
339.41
Molecular Formula:
C16H21NO5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Moguisteine is an antitussive with properties similar to codeine. The antitussive activity may stem from interactions with ATP-sensitive K+ channels.
Moguisteine (CAS 119637-67-1) References
- Involvement of ATP-sensitive K(+) channels in the anti-tussive effect of moguisteine. | Morita, K. and Kamei, J. 2000. Eur J Pharmacol. 395: 161-4. PMID: 10794823
- Inhaled pinacidil, an ATP-sensitive K+ channel opener, and moguisteine have potent antitussive effects in guinea pigs. | Morita, K., et al. 2002. Jpn J Pharmacol. 89: 171-5. PMID: 12120760
- Currently available cough suppressants for chronic cough. | Chung, KF. 2008. Lung. 186 Suppl 1: S82-7. PMID: 17909897
- Levodropropizine in the management of cough associated with cancer or nonmalignant chronic disease--a systematic review. | Schildmann, EK., et al. 2011. J Pain Palliat Care Pharmacother. 25: 209-18. PMID: 21806417
- Single- and multiple-dose pharmacokinetics of the peripheral non-narcotic antitussive moguisteine in healthy Chinese volunteers. | Gou, ZP., et al. 2019. Eur J Pharm Sci. 130: 166-172. PMID: 30703444
- Moguisteine: a novel peripheral non-narcotic antitussive drug. | Gallico, L., et al. 1994. Br J Pharmacol. 112: 795-800. PMID: 7921605
- Assay of moguisteine metabolites in human plasma and urine: conventional and chiral high-performance liquid chromatographic methods. | Castoldi, D., et al. 1994. J Chromatogr B Biomed Appl. 655: 243-52. PMID: 8081470
- Effects of moguisteine, a peripheral nonnarcotic antitussive agent, on airway inflammation in guinea-pigs in vivo. | Gallico, L., et al. 1996. Eur Respir J. 9: 478-85. PMID: 8730007
- Antitussive effect of moguisteine on the enhanced coughing associated with enalapril in guinea-pig. | Kamei, J. and Morita, K. 1996. Eur J Pharmacol. 312: 235-9. PMID: 8894601
- Stereoselective pharmacokinetics of moguisteine metabolites in healthy subjects. | Bernareggi, A., et al. 1995. Eur J Drug Metab Pharmacokinet. 20: 263-70. PMID: 8983930
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Moguisteine, 100 mg | sc-204810 | 100 mg | $70.00 | |||
Moguisteine, 250 mg | sc-204810A | 250 mg | $150.00 |