Date published: 2026-5-16

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Mn(III) Protoporphyrin IX chloride (CAS 120389-54-0)

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Alternate Names:
8,13-Bis(vinyl)-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid manganese(III) chloride
Application:
Mn(III) Protoporphyrin IX chloride is Mn(III) Protoporphyrin IX chloride is useful in the study of hemoglobin and porphyrins
CAS Number:
120389-54-0
Molecular Weight:
651.03
Molecular Formula:
C34H32ClMnN4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Mn(III) Protoporphyrin IX chloride is a manganese-containing porphyrin complex, known primarily for its utility in biochemical studies related to the understanding of redox reactions and oxygen transport mechanisms in biological systems. This compound acts as a potent mimic of natural heme environments, facilitating the study of heme-protein interactions and the catalytic roles of metalloenzymes. Its distinctive redox properties make it particularly valuable in examining electron transfer processes, which are in cellular respiration and photosynthesis. Researchers utilize Mn(III) Protoporphyrin IX chloride extensively in spectroscopic studies, where its interaction with light provides insights into the dynamics of metal coordination complexes under various conditions. This facilitates a deeper understanding of the structural and functional dynamics of metalloproteins, contributing significantly to advancements in biochemical and biophysical research.


Mn(III) Protoporphyrin IX chloride (CAS 120389-54-0) References

  1. Synthesis and reactivity studies of a manganese 'microperoxidase' containing b-type heme.  |  Ryabova, ES. and Nordlander, E. 2005. Dalton Trans. 1228-33. PMID: 15782258
  2. Crystal structures of manganese- and cobalt-substituted myoglobin in complex with NO and nitrite reveal unusual ligand conformations.  |  Zahran, ZN., et al. 2008. J Inorg Biochem. 102: 216-33. PMID: 17905436
  3. Cytochrome b5 inhibits electron transfer from NADPH-cytochrome P450 reductase to ferric cytochrome P450 2B4.  |  Zhang, H., et al. 2008. J Biol Chem. 283: 5217-25. PMID: 18086668
  4. Redox transitions of chromium, manganese, iron, cobalt and nickel protoporphyrins in aqueous solution.  |  de Groot, MT. and Koper, MT. 2008. Phys Chem Chem Phys. 10: 1023-31. PMID: 18259642
  5. An Escherichia coli expression-based approach for porphyrin substitution in heme proteins.  |  Winter, MB., et al. 2013. Methods Mol Biol. 987: 95-106. PMID: 23475670
  6. Fe- but not Mg-protophorphyrin IX binds to a transmembrane b-type cytochrome.  |  Tome, L., et al. 2014. Mol Membr Biol. 31: 37-45. PMID: 24328791
  7. PPE37 Is Essential for Mycobacterium tuberculosis Heme-Iron Acquisition (HIA), and a Defective PPE37 in Mycobacterium bovis BCG Prevents HIA.  |  Tullius, MV., et al. 2019. Infect Immun. 87: PMID: 30455201
  8. A Review on (Hydro)Porphyrin-Loaded Polymer Micelles: Interesting and Valuable Platforms for Enhanced Cancer Nanotheranostics.  |  Nascimento, BFO., et al. 2019. Pharmaceutics. 11: PMID: 30769938
  9. Noninvasively immunogenic sonodynamic therapy with manganese protoporphyrin liposomes against triple-negative breast cancer.  |  Chen, H., et al. 2021. Biomaterials. 269: 120639. PMID: 33434714

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Mn(III) Protoporphyrin IX chloride, 250 mg

sc-396877
250 mg
$312.00

Mn(III) Protoporphyrin IX chloride, 1 g

sc-396877A
1 g
$894.00