Molecular structure of MMP-3 Inhibitor III
MMP-3 Inhibitor III
See product citations (2)
Alternate Names:
N-[[(4,5-Dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)amino]carbonyl]-L-phenylalanine
Application:
MMP-3 Inhibitor III is a potent MMP-3 inhibitor with some MMP-2 inhibitory activity
Purity:
≥95%
Molecular Weight:
324.4
Molecular Formula:
C12H12N4O3S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
MMP-3 Inhibitor III is a potent inhibitor of MMP-3 (Ki = 3.2 μM) and inhibits MMP-2 only at higher concentrations (Ki >200 μM).
MMP-3 Inhibitor III References
- Synthesis of a series of stromelysin-selective thiadiazole urea matrix metalloproteinase inhibitors. | Jacobsen, EJ., et al. 1999. J Med Chem. 42: 1525-36. PMID: 10229623
- MMP-3 (5A/6A) polymorphism does not influence human smooth muscle cell invasion. | Maqbool, A., et al. 2012. J Surg Res. 175: 343-9. PMID: 21601886
- ERα signaling regulates MMP3 expression to induce FasL cleavage and osteoclast apoptosis. | Garcia, AJ., et al. 2013. J Bone Miner Res. 28: 283-90. PMID: 22927007
Inhibitor of:
Enzyme, and MMP-3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MMP-3 Inhibitor III, 2 mg | sc-311432 | 2 mg | $300.00 |