Molecular structure of MMP-2/MMP-3 Inhibitor I
MMP-2/MMP-3 Inhibitor I
See product citations (3)
Alternate Names:
N-[[(4,5-Dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)amino]carbonyl]-L-phenylalanine Methyl Ester
Application:
MMP-2/MMP-3 Inhibitor I is a potent inhibitor of MMP-2 and MMP-3
Molecular Weight:
338.4
Molecular Formula:
C13H14N4O3S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
MMP-8 Inhibitor I is a potent MMP-2 (gelatinase A; Ki = 17 μM) and MMP-3 (stromelysin-1; Ki = 290 nM) inhibitor.
MMP-2/MMP-3 Inhibitor I References
- Synthesis of a series of stromelysin-selective thiadiazole urea matrix metalloproteinase inhibitors. | Jacobsen, EJ., et al. 1999. J Med Chem. 42: 1525-36. PMID: 10229623
- Effects of extracellular matrix-degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic plasticity. | Meighan, SE., et al. 2006. J Neurochem. 96: 1227-41. PMID: 16464240
- Matrix metalloproteinase activity assays: Importance of zymography. | Kupai, K., et al. 2010. J Pharmacol Toxicol Methods. 61: 205-9. PMID: 20176119
- Identifying simultaneous matrix metalloproteinases/soluble epoxide hydrolase inhibitors. | El-Sherbeni, AA., et al. 2022. Mol Cell Biochem. 477: 877-884. PMID: 35067781
Inhibitor of:
MMP-2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MMP-2/MMP-3 Inhibitor I, 5 mg | sc-295483 | 5 mg | $240.00 |