MM-142 Cell Lysate: sc-2246

MM-142 cell lysate is derived from a specific cell line frequently utilized in research contexts to investigate cellular responses to various stimuli, including stress, drug exposure, and genetic manipulation. The lysate itself is rich in cellular contents such as proteins, nucleic acids, and organelle fragments, which offer a snapshot of the cell's state under specific conditions. Scientifically, MM-142 cell lysate is particularly valued for its application in proteomics and molecular biology studies. For instance, researchers use this lysate in mass spectrometry to identify and quantify proteins that are upregulated or downregulated under different experimental conditions, providing insights into protein expression patterns and potential signaling pathways involved. Additionally, MM-142 cell lysate serves as a critical component in Western blotting protocols to validate the presence of target proteins and to examine post-translational modifications, such as phosphorylation or ubiquitination. These applications are crucial for understanding the mechanistic underpinnings of cellular functions and for exploring the molecular basis of cellular behavior in response to various experimental treatments. This lysate is used to advance basic scientific knowledge and to decipher cellular mechanisms at a molecular level.

MM-142 Cell Lysate References:

1. Follicle stimulating hormone-induced DNA synthesis in the granulosa cells of hamster preantral follicles involves activation of cyclin-dependent kinase-4 rather than cyclin d2 synthesis.  |  Yang, P. and Roy, SK. 2004. Biol Reprod. 70: 509-17. PMID: 14561638