MK-912 hydrate (CAS 119942-70-0 (anhydrous))
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MK-912 hydrate functions as a selective and potent antagonist of the dopamine D3 receptor. It acts by binding to the D3 receptor and inhibiting its activation by endogenous dopamine. This interaction modulates the transmission of dopamine signaling in the brain, affecting various physiological and behavioral processes. Mk-912 hydrate′s mechanism of action involves blocking the binding of dopamine to the D3 receptor, thereby altering the downstream signaling cascades and neuronal activity. In experimental applications, MK-912 hydrate is utilized to investigate the role of the dopamine D3 receptor in various neurological and psychiatric conditions, providing insights into the molecular mechanisms underlying these disorders. Its specific interaction with the D3 receptor may be useful in studying the function of this receptor subtype and its potential implications in the modulation of dopamine-related pathways.
MK-912 hydrate (CAS 119942-70-0 (anhydrous)) References
- Functional role of alpha2-adrenoceptor subtypes in the cooling-enhanced vasoconstriction of isolated cutaneous digital veins of the horse. | Zerpa, H., et al. 2010. Eur J Pharmacol. 627: 194-202. PMID: 19878669
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MK-912 hydrate, 5 mg | sc-253050 | 5 mg | $169.00 |