Molecular structure of MK 212 hydrochloride, CAS Number: 64022-27-1
MK 212 hydrochloride (CAS 64022-27-1)
Alternate Names:
6-chloro-2-(1-piperazinyl)pyrazine, monohydrochloride
Application:
MK 212 hydrochloride is a SR-2C agonist
CAS Number:
64022-27-1
Purity:
≥99%
Molecular Weight:
235.12
Molecular Formula:
C8H11CIN4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
MK 212 hydrochloride is a SR-2C agonist.
MK 212 hydrochloride (CAS 64022-27-1) References
- Inhibition of rat nucleus tractus solitarius neurones by activation of 5-HT2C receptors. | Sévoz-Couche, C., et al. 2000. Neuroreport. 11: 1785-90. PMID: 10852245
- In vivo modulation of vagal-identified dorsal medullary neurones by activation of different 5-Hydroxytryptamine(2) receptors in rats. | Sévoz-Couche, C., et al. 2000. Br J Pharmacol. 131: 1445-53. PMID: 11090119
- Serotonin(2) receptors mediate respiratory recovery after cervical spinal cord hemisection in adult rats. | Zhou, SY., et al. 2001. J Appl Physiol (1985). 91: 2665-73. PMID: 11717232
- Serotonin receptors involved in vasopressin and oxytocin secretion. | Jørgensen, H., et al. 2003. J Neuroendocrinol. 15: 242-9. PMID: 12588512
- Discriminative stimulus properties of (+/-)-fenfluramine: the role of 5-HT2 receptor subtypes. | McCreary, AC., et al. 2003. Behav Neurosci. 117: 212-21. PMID: 12708517
- Effect of 5HT2C-receptor agonist MK-212 on blood corticosterone level and behavior in mice. | Kuznetsova, EG., et al. 2006. Bull Exp Biol Med. 142: 594-7. PMID: 17415471
- Role of dopamine D(1)-family receptors in dorsolateral striatum in context-induced reinstatement of heroin seeking in rats. | Bossert, JM., et al. 2009. Psychopharmacology (Berl). 206: 51-60. PMID: 19506837
- Novel approach to data analysis in cocaine-conditioned place preference. | dela Cruz, AM., et al. 2009. Behav Pharmacol. 20: 720-30. PMID: 19901823
- Discriminative stimulus effects of serotonin agonists, neutral antagonists, and inverse agonists in pigeons: perspectives on intrinsic efficacy measurements in vivo. | Farrell, M., et al. 2010. Psychopharmacology (Berl). 211: 149-59. PMID: 20526585
- Spontaneous rhythmogenic capabilities of sympathetic neuronal assemblies in the rat spinal cord slice. | Pierce, ML., et al. 2010. Neuroscience. 170: 827-38. PMID: 20650307
- [Agonists of 5HT2C-receptors SCH 23390 and MK 212 incresase the force of rat aorta contraction in the presence of vasopressin and angiotensin II]. | Kozhevnikova, LM., et al. 2014. Patol Fiziol Eksp Ter. 17-29. PMID: 25980223
- Selective Serotonin Reuptake Inhibitors and 5-HT2 Receptor Agonists Have Distinct, Sleep-state Dependent Effects on Postictal Breathing in Amygdala Kindled Mice. | Joyal, KG., et al. 2023. Neuroscience. 513: 76-95. PMID: 36702372
- Effect of pindolol pretreatment on MK-212-induced plasma cortisol and prolactin responses in normal men. | Meltzer, HY. and Maes, M. 1995. Biol Psychiatry. 38: 310-8. PMID: 7495925
Activator of:
Serotonin, and SR-2C.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MK 212 hydrochloride, 10 mg | sc-203634 | 10 mg | $115.00 | |||
MK 212 hydrochloride, 50 mg | sc-203634A | 50 mg | $473.00 |