Date published: 2026-5-23

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MK 0524 sodium salt (CAS 572874-50-1)

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Alternate Names:
Laropiprant
Application:
MK 0524 sodium salt is a potent, selective DP1 receptor antagonist
CAS Number:
572874-50-1
Molecular Weight:
457.88
Molecular Formula:
C21H18ClFNO4SNa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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MK 0524 unique molecular structure allows for its utilization in the study of chemical interactions and reactions. In a laboratory setting, MK 0524 is often used as a reference compound to understand the binding affinities of molecular targets. Researchers also employ MK 0524 in the development and calibration of analytical methods, which are for the accurate measurement of chemical properties. Furthermore, it plays a role in the synthesis of complex molecules, serving as a building block in the creation of new compounds with diverse chemical functionalities. The impact of MK 0524 extends to materials science, where it is used to explore the fabrication of novel materials with potential applications.


MK 0524 sodium salt (CAS 572874-50-1) References

  1. The DP receptor, allergic inflammation and asthma.  |  Kabashima, K. and Narumiya, S. 2003. Prostaglandins Leukot Essent Fatty Acids. 69: 187-94. PMID: 12895602
  2. Positioning prostanoids of the D and J series in the immunopathogenic scheme.  |  Herlong, JL. and Scott, TR. 2006. Immunol Lett. 102: 121-31. PMID: 16310861
  3. Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans.  |  Cheng, K., et al. 2006. Proc Natl Acad Sci U S A. 103: 6682-7. PMID: 16617107
  4. Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524).  |  Sturino, CF., et al. 2007. J Med Chem. 50: 794-806. PMID: 17300164
  5. Metabolic fate of endogenously synthesized prostaglandin D2 in a human female with mastocytosis.  |  Roberts, LJ. and Sweetman, BJ. 1985. Prostaglandins. 30: 383-400. PMID: 3864190

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

MK 0524 sodium salt, 1 mg

sc-205391
1 mg
$106.00

MK 0524 sodium salt, 5 mg

sc-205391A
5 mg
$296.00