Molecular structure of Misoprostol (free acid)-d5, CAS Number: 1337917-44-8
Misoprostol (free acid)-d5 (CAS 1337917-44-8)
Alternate Names:
9-oxo-11α,16-dihydroxy-16-(methyl-d3)-prost-13E-en-1-oic-17,17-d2 acid
Application:
Misoprostol (free acid)-d5 is a deuterated version of PGE1 with agonist activity mediated by EP2, EP3, and EP4
CAS Number:
1337917-44-8
Purity:
≥99% deuterated forms (d1-d5)
Molecular Weight:
373.5
Molecular Formula:
C21H31D5O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Misoprostol (free acid)-d5 is a deuterium labeled version of Misoprostol, free acid, (sc-205390), a synthetic E prostaglandin, that has been shown to prevent tissue corrosion induced by certain anti-inflammatory compounds. Additionally, this compound has been shown to have negative effects on the murine nervous system by altering the intracellular calcium levels in neuroblastoma cells. Other experiments have noted that Misoprostol has the ability to affect serum concentration of β2-microglobulin, which is related to antigen presentation on hepatocyte surface.
Misoprostol (free acid)-d5 (CAS 1337917-44-8) References
- Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial. | Graham, DY., et al. 1988. Lancet. 2: 1277-80. PMID: 2904006
- Pharmacokinetics and ex vivo anti-inflammatory effects of oral misoprostol in horses. | Martin, EM., et al. 2019. Equine Vet J. 51: 415-421. PMID: 30256450
- Intravaginal misoprostol versus dinoprostone as cervical ripening and labor-inducing agents. | Fletcher, H., et al. 1994. Obstet Gynecol. 83: 244-7. PMID: 8290188
- Duodenal and gastric ulcer prevention with misoprostol in arthritis patients taking NSAIDs. Misoprostol Study Group. | Graham, DY., et al. 1993. Ann Intern Med. 119: 257-62. PMID: 8328732
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Misoprostol (free acid)-d5, 50 µg | sc-221944 | 50 µg | $121.00 | |||
Misoprostol (free acid)-d5, 100 µg | sc-221944A | 100 µg | $186.00 | |||
Misoprostol (free acid)-d5, 1 mg | sc-221944B | 1 mg | $631.00 | |||
Misoprostol (free acid)-d5, 5 mg | sc-221944C | 5 mg | $3126.00 | |||
Misoprostol (free acid)-d5, 10 mg | sc-221944D | 10 mg | $5935.00 | |||
Misoprostol (free acid)-d5, 25 mg | sc-221944E | 25 mg | $13946.00 |