Molecular structure of Misoprostol (free acid), CAS Number: 112137-89-0
Misoprostol (free acid) (CAS 112137-89-0)
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Alternate Names:
9-oxo-11α,16-dihydroxy-16-methyl-prost-13E-en-1-oic acid
Application:
Misoprostol (free acid) is a PGE1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors
CAS Number:
112137-89-0
Purity:
≥97%
Molecular Weight:
368.5
Molecular Formula:
C21H36O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Misoprostol, a synthetic E prostaglandin, has been shown to prevent tissue corrosion induced by certain anti-inflammatory compounds. Additionally, This compound has been shown to have negative effects on the murine nervous system by altering the intracellular calcium levels in neuroblastoma cells. Other experiments have noted that Misoprostol has the ability to affect serum concentration of β2-microglobulin, which is related to antigen presentation on hepatocyte surface.
Misoprostol (free acid) (CAS 112137-89-0) References
- Effect of misoprostol on serum beta2-microglobulin in the course of viral hepatitis B. | Flisiak, R. and Prokopowicz, D. 1999. Eur J Gastroenterol Hepatol. 11: 1227-30. PMID: 10563531
- Misoprostol therapeutics revisited. | Davies, NM., et al. 2001. Pharmacotherapy. 21: 60-73. PMID: 11191738
- Misoprostol in the prevention of postpartum hemorrhage. | Mategrano, VA. and Gabay, MP. 2001. Ann Pharmacother. 35: 1648-52. PMID: 11793636
- Maternal death related to misoprostol overdose. | Henriques, A., et al. 2007. Obstet Gynecol. 109: 489-90. PMID: 17267868
- Misoprostol: pharmacokinetic profiles, effects on the uterus and side-effects. | Tang, OS., et al. 2007. Int J Gynaecol Obstet. 99 Suppl 2: S160-7. PMID: 17963768
- Misoprostol elevates intracellular calcium in Neuro-2a cells via protein kinase A. | Tamiji, J. and Crawford, DA. 2010. Biochem Biophys Res Commun. 399: 565-70. PMID: 20678471
- Misoprostol in operative hysteroscopy: a systematic review and meta-analysis. | Selk, A. and Kroft, J. 2011. Obstet Gynecol. 118: 941-9. PMID: 21934459
- Misoprostol to reduce intraoperative and postoperative hemorrhage during cesarean delivery: a systematic review and metaanalysis. | Conde-Agudelo, A., et al. 2013. Am J Obstet Gynecol. 209: 40.e1-40.e17. PMID: 23507545
- Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial. | Graham, DY., et al. 1988. Lancet. 2: 1277-80. PMID: 2904006
- Oral misoprostol tablets (25 µg) for induction of labor: a targeted literature review and cost analysis. | Poinas, AC., et al. 2022. J Med Econ. 25: 428-436. PMID: 35297743
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Misoprostol (free acid), 1 mg | sc-205390 | 1 mg | $72.00 | |||
Misoprostol (free acid), 5 mg | sc-205390A | 5 mg | $244.00 |