Date published: 2026-2-2

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(−)Scopolamine methyl nitrate (CAS 6106-46-3)

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Alternate Names:
Methscopolamine Nitrate; Hyoscine methyl nitrate
Application:
(−)Scopolamine methyl nitrate is a competitive antimuscarinic agent
CAS Number:
6106-46-3
Purity:
98%
Molecular Weight:
380.39
Molecular Formula:
C17H21NO4•CH3NO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(−)Scopolamine methyl nitrate is a competitive antimuscarinic agent, blocking the binding of acetylcholine at mAChR M and preventing the opening of ion channels. (−)Scopolamine methyl nitrate is a versatile chemical compound extensively employed in scientific research for its broad range of applications. As a nitrate ester derived from the tertiary amine methscopolamine, it plays a role in numerous chemical processes. Its utility extends across various industries, including pharmaceuticals, agricultural chemicals, and food processing. Notably, (−)Scopolamine methyl nitrate offers several advantages, such as its cost-effectiveness, widespread availability, and remarkable stability. It serves as a valuable reagent for organic synthesis, an intermediate for synthesizing diverse compounds, and a valuable analytical tool. Additionally, it finds application in the exploration of enzyme kinetics and the investigation of drug metabolism.


(−)Scopolamine methyl nitrate (CAS 6106-46-3) References

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  2. Effects of biasing the location of stimulus presentation, and the muscarinic cholinergic receptor antagonist scopolamine, on performance of a 5-choice serial reaction time attention task in rats.  |  Shannon, HE. and Eberle, EL. 2006. Behav Pharmacol. 17: 71-85. PMID: 16377965
  3. Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus.  |  Kong, Q., et al. 2012. Neurobiol Dis. 47: 145-54. PMID: 22513140
  4. Status epilepticus alters hippocampal long-term synaptic potentiation in a rat lithium-pilocarpine model.  |  Kryukov, KA., et al. 2016. Neuroreport. 27: 1191-5. PMID: 27495218
  5. Synergistic action of CB1 and 5-HT2B receptors in preventing pilocarpine-induced status epilepticus in rats.  |  Colangeli, R., et al. 2019. Neurobiol Dis. 125: 135-145. PMID: 30716469
  6. Reactive pericytes in early phase are involved in glial activation and late-onset hypersusceptibility to pilocarpine-induced seizures in traumatic brain injury model mice.  |  Sakai, K., et al. 2021. J Pharmacol Sci. 145: 155-165. PMID: 33357774
  7. Preferential neuronal loss in layer III of the medial entorhinal cortex in rat models of temporal lobe epilepsy.  |  Du, F., et al. 1995. J Neurosci. 15: 6301-13. PMID: 7472396
  8. Intracerebroventricular pertussis toxin enhances sensitivity to chemical convulsants and decreases the protective efficacy of carbamazepine in mice.  |  Korolkiewicz, R., et al. 1996. Pharmacol Res. 33: 211-5. PMID: 8880893

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(−)Scopolamine methyl nitrate, 1 g

sc-264301
1 g
$181.00

(−)Scopolamine methyl nitrate, 5 g

sc-264301A
5 g
$525.00