Molecular structure of Milbemycin D, CAS Number: 77855-81-3
Milbemycin D (CAS 77855-81-3)
See product citations (2)
Alternate Names:
Antibiotic B 41D
Application:
Milbemycin D is a potent nematocide and insecticide
CAS Number:
77855-81-3
Purity:
>95%
Molecular Weight:
556.7
Molecular Formula:
C33H48O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Milbemycin D is a highly selective and potent nematocide. Although a minor member, it belongs to a group of analogues that have a 25-isopropyl substituent. The milbemycins are part of a family of macrocyclic lactones that are characterized by the spiroketal ring system that were produced by Streptomyces hydroscopious subsp. aureolarcrimosus and are believed to stimulate chloride-gated ion channels.
Milbemycin D (CAS 77855-81-3) References
- Macrolide compounds, ivermectin and milbemycin D, stimulate chloride channels sensitive to GABAergic drugs in cultured chick spinal neurons. | Yamazaki, J., et al. 1989. Comp Biochem Physiol C Comp Pharmacol Toxicol. 93: 97-104. PMID: 2471607
- Engineered biosynthesis of milbemycins in the avermectin high-producing strain Streptomyces avermitilis. | Kim, MS., et al. 2017. Microb Cell Fact. 16: 9. PMID: 28095865
- Milbemycins, a new family of macrolide antibiotics. Fermentation, isolation and physico-chemical properties of milbemycins D, E, F, G, and H. | Takiguchi, Y., et al. 1983. J Antibiot (Tokyo). 36: 502-8. PMID: 6874568
- Avermectin/milbemycin resistance in trichostrongyloid nematodes. | Gill, JH. and Lacey, E. 1998. Int J Parasitol. 28: 863-77. PMID: 9673866
- Biotransformation of milbemycin D to milemycin G by Streptomyces lividans conferring avermectin O-methyltransferase activity | Young-Soo Hong, Bang Yeon Hwang, Hang Sub Kim, Jeong-hyung Lee, Kyu-Won Kim & Jung Joon Lee. 1998. Biotechnology Letters. 20: 991–995.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Milbemycin D, 1 mg | sc-202228 | 1 mg | $395.00 | |||
Milbemycin D, 1 mg | sc-202228-CW | 1 mg | $793.00 | |||
Milbemycin D, 5 mg | sc-202228A | 5 mg | $1375.00 |