MIA PaCa-2 Cell Lysate: sc-2285

MIA PaCa-2 cell lysate is derived from a well-characterized pancreatic adenocarcinoma cell line used extensively in cancer research to explore cellular mechanisms and signaling pathways relevant to cancer biology. The lysate contains a complete profile of cellular proteins, making it an invaluable resource for proteomic analyses and biochemical assays aimed at understanding cancer cell behaviors under various experimental conditions. Researchers utilize this lysate to study gene expression patterns and protein-protein interactions, especially focusing on pathways such as KRAS signaling, which is notoriously active in pancreatic cancer. The MIA PaCa-2 lysate helps in identifying potential oncogenic drivers and in elucidating mechanisms of resistance to conventional treatments. In molecular biology laboratories, the lysate is also used to validate the efficacy of signal transduction inhibitors in preclinical studies, providing insights into the cellular response to different biochemical modulators. This research application aids in the broader understanding of cellular adaptations in cancer. Moreover, the lysate serves as a tool in the development of novel diagnostic markers by enabling the comparative analysis of protein expressions between cancerous and non-cancerous cell states, thus contributing fundamentally to cancer biology research.

MIA PaCa-2 Cell Lysate References:

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