Molecular structure of MHY1485, CAS Number: 326914-06-1
MHY1485 (CAS 326914-06-1)
CAS Number:
326914-06-1
Molecular Weight:
387.4
Molecular Formula:
C17H21N7O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
MHY1485 (CAS 326914-06-1) References
- MHY1485 activates mTOR and protects osteoblasts from dexamethasone. | Zhao, S., et al. 2016. Biochem Biophys Res Commun. 481: 212-218. PMID: 27884298
- MHY1485 ameliorates UV-induced skin cell damages via activating mTOR-Nrf2 signaling. | Yang, B., et al. 2017. Oncotarget. 8: 12775-12783. PMID: 28061443
- Tanshinone IIA protects against heart failure post-myocardial infarction via AMPKs/mTOR-dependent autophagy pathway. | Zhang, X., et al. 2019. Biomed Pharmacother. 112: 108599. PMID: 30798134
- MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint. | Yang, H., et al. 2020. Autophagy. 16: 271-288. PMID: 31007149
- MHY1485 enhances X-irradiation-induced apoptosis and senescence in tumor cells. | Sun, L., et al. 2021. J Radiat Res. 62: 782-792. PMID: 34265852
- Fluoride regulates chondrocyte proliferation and autophagy via PI3K/AKT/mTOR signaling pathway. | Ma, L., et al. 2021. Chem Biol Interact. 349: 109659. PMID: 34536393
- Dihydromyricetin Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting SPHK1/mTOR Signaling and Targeting Ferroptosis. | Xie, J., et al. 2022. Drug Des Devel Ther. 16: 3071-3085. PMID: 36118165
- Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling. | Wang, G., et al. 2023. Cell Death Dis. 14: 292. PMID: 37185889
- Intracerebroventricular Injection of MHY1485 Blocked the Beneficial Effect of Adiponectin on Aversive Memory in the STZ Model of Dementia. | Rashtiani, S., et al. 2023. Cent Nerv Syst Agents Med Chem.. PMID: 37723956
- MHY1485 potentiates immunogenic cell death induction and anti-cancer immunity following irradiation. | Sun, L., et al. 2024. J Radiat Res. 65: 205-214. PMID: 38330507
Inhibitor of:
AMBRA1, APG5, Atg13, Atg16, Atg3, Atg9a, C11orf74, C12orf44, ERRβ, IFT20, KIAA0652, MAP LC3α, Ribosomal Protein L13A, Syntaxin 17, TBC1D5, TRIM16, ULK2, and WIPI-4.Activator of:
BC024814, Dok-1, hamartin, Helios, HEXDC, IL-13Rα2, IRX3, KNDC1, LOC728677, MLSN1, Orf Virus, PDK2, PROT, RAI15, Ribosomal Protein S25, SPT5, TFR2, TIGD7, TMEM170, and VPS25.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MHY1485, 10 mg | sc-507522 | 10 mg | $140.00 |