MFSD1 Antibody (A-11): sc-398710

MFSD1 Antibody (A-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects MFSD1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MFSD1 (A-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The Major Facilitator Superfamily, to which MFSD1 belongs, is characterized by its presumed role in carbohydrate transport, featuring 10-12 membrane-spanning domains that facilitate the movement of substrates across cellular membranes. MFSD1, also known as Smooth Muscle Cell-Associated Protein 4, is a 465 amino acid multi-pass membrane protein that exists in two isoforms due to alternative splicing. MFSD1 plays a crucial role in cellular transport mechanisms, which are vital for maintaining cellular homeostasis and responding to metabolic demands. The gene encoding MFSD1 is located on human chromosome 3, a region associated with various genetic disorders, including Marfan Syndrome and Charcot-Marie-Tooth Disease, highlighting the importance of MFSD1 in both normal physiology and disease states. Understanding the function and interactions of MFSD1 can provide insights into its potential roles in health and disease, making anti-MFSD1 antibody (A-11) an essential tool for researchers studying these pathways.

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MFSD1 Antibody (A-11) References:

1. Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution.  |  Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
2. [New tumor suppressor genes in hot spots of human chromosome 3: new methods of identification].  |  Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
3. The DNA sequence, annotation and analysis of human chromosome 3.  |  Muzny, DM., et al. 2006. Nature. 440: 1194-8. PMID: 16641997
4. Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis.  |  Angers, M., et al. 2008. Biochem J. 416: 347-55. PMID: 18694395
5. Evolutionary plasticity and cancer breakpoints in human chromosome 3.  |  Ruiz-Herrera, A. and Robinson, TJ. 2008. Bioessays. 30: 1126-37. PMID: 18937354
6. Bacterial multidrug transport through the lens of the major facilitator superfamily.  |  Fluman, N. and Bibi, E. 2009. Biochim Biophys Acta. 1794: 738-47. PMID: 19103310
7. The secondary multidrug/proton antiporter MdfA tolerates displacements of an essential negatively charged side chain.  |  Sigal, N., et al. 2009. J Biol Chem. 284: 6966-71. PMID: 19129186

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-MFSD1 Antibody (A-11) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-MFSD1 Antibody (A-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

MFSD1 Antibody (A-11) Specifications

Alternate Product Name: MFSD1

Product Clone Name: A-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 434-458

Epitope Target: MFSD1

Epitope Species: human

Product Reactivity/Detection: MFSD1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for MFSD1 Antibody (A-11): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin