Date published: 2025-10-14

1-800-457-3801

SCBT Portrait Logo
Seach Input

Mezlocillin (CAS 51481-65-3)

0.0(0)
Write a reviewAsk a question

Alternate Names:
Mezlin; Mezlocilina; Mezlocillinum
Application:
Mezlocillin is a broad spectrum penicillin antibiotic
CAS Number:
51481-65-3
Purity:
97%
Molecular Weight:
539.58
Molecular Formula:
C21H25N5O8S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Mezlocillin, identified by the CAS number 51481-65-3, is a synthetic penicillin derivative known for its broad-spectrum activity, which has been the subject of various non-clinical research studies focusing on its chemical properties and environmental interactions. In the realm of environmental science, mezlocillin has been studied for its biodegradability and the mechanisms through which it breaks down in various environmental settings, such as soil and water systems. Researchers utilize advanced analytical methods, including chromatography and spectroscopy, to monitor the degradation pathways of mezlocillin and to identify its metabolites. This is crucial for understanding how such substances disperse and transform in the environment, which can inform environmental risk assessments and strategies for minimizing ecological impact. Additionally, mezlocillin has served as a model compound in studies aimed at improving wastewater treatment processes, where its removal efficiency can be tested against various treatment technologies. In chemical research, mezlocillin is used to explore the stability of beta-lactam rings under different conditions, contributing to the broader knowledge of chemical stability and reactivity that can be applied to similar compounds. Through these studies, mezlocillin helps in advancing our understanding of environmental chemistry and the sustainable management of chemical substances in ecosystems.


Mezlocillin (CAS 51481-65-3) References

  1. In vitro activity of mezlocillin, meropenem, aztreonam, vancomycin, teicoplanin, ribostamycin and fusidic acid against Borrelia burgdorferi.  |  Hunfeld, KP., et al. 2001. Int J Antimicrob Agents. 17: 203-8. PMID: 11282265
  2. Effect of daptomycin, metronidazole and mezlocillin combinations on mixed bacterial cultures involving facultative and anaerobic bacteria.  |  Nagy, E., et al. 1991. Scand J Infect Dis. 23: 239-45. PMID: 1649493
  3. Dose-dependent pharmacokinetics of mezlocillin in rats.  |  Jungbluth, GL. and Jusko, WJ. 1989. Antimicrob Agents Chemother. 33: 839-43. PMID: 2764534
  4. Azlocillin and mezlocillin concentration in human prostatic tissue.  |  Smith, RP., et al. 1988. Chemotherapy. 34: 267-71. PMID: 3208544
  5. Development and Validation of a UPLC-MS/MS Method for Ultra-Trace Level Determination of Acyl Chloride Potential Genotoxic Impurity in Mezlocillin.  |  Chen, Y., et al. 2022. J Chromatogr Sci. 60: 732-740. PMID: 34718453
  6. Behaviour of TEM-1 beta-lactamase as a resistance mechanism to ampicillin, mezlocillin and azlocillin in Escherichia coli.  |  Livermore, DM., et al. 1986. J Antimicrob Chemother. 17: 139-46. PMID: 3516962
  7. Mezlocillin, ceftizoxime, and amikacin alone and in combination against six Enterobacteriaceae in a neutropenic site in rabbits.  |  Gerding, DN., et al. 1985. J Antimicrob Chemother. 15 Suppl A: 207-19. PMID: 3856563
  8. Effects of cefotaxime, clindamycin, mezlocillin, and piperacillin on mouse sarcoma L-1 tumor.  |  Roszkowski, K., et al. 1984. Cancer Immunol Immunother. 18: 164-8. PMID: 6095992
  9. Comparative efficacies of mezlocillin and ampicillin alone or in combination with gentamicin in the treatment of Streptococcus faecalis endocarditis in rabbits.  |  Fass, RJ. and Wright, CA. 1984. Antimicrob Agents Chemother. 25: 408-10. PMID: 6428306
  10. Mezlocillin enteral absorption in rabbits.  |  Lavelle, KJ., et al. 1981. Antimicrob Agents Chemother. 20: 418-9. PMID: 6458237

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Mezlocillin, 1 g

sc-279447
1 g
$700.00