Date published: 2025-12-18

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Methyltrioctadecylammonium bromide (CAS 18262-86-7)

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Alternate Names:
Trioctadecylmethylammonium bromide
Application:
Methyltrioctadecylammonium bromide is an anion exchange ionophore for perchlorate-selective membranes
CAS Number:
18262-86-7
Molecular Weight:
869.42
Molecular Formula:
C55H114BrN
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyltrioctadecylammonium bromide, also referred to as MTOAB or MTODAB, is a quaternary ammonium salt in laboratory experiments. Methyltrioctadecylammonium bromide is a long chain ionophore in anion exchange for perchlorate-selective membranes. Methyltrioctadecylammonium bromide finds utility in diverse applications. It has been utilized to investigate protein-protein interactions, ion channels, and enzyme-substrate interactions. It contributes to studying the structure and functionality of cell membranes, including ion transport across them. The mechanism of action of Methyltrioctadecylammonium bromide involves the formation of a cationic lipid layer on the cell surface. This lipid layer acts as a protective barrier, preventing the entry of foreign molecules into the cell.Methyltrioctadecylammonium bromide has the ability to interact with specific proteins on the cell surface, leading to the formation of complexes that can modulate the cell′s physiology.


Methyltrioctadecylammonium bromide (CAS 18262-86-7) References

  1. Surface complexation of DNA with insoluble monolayers. Influence of divalent counterions.  |  McLoughlin, D., et al. 2005. Langmuir. 21: 1900-7. PMID: 15723487
  2. Modification of the surfaces of Wyoming montmorillonite by the cationic surfactants alkyl trimethyl, dialkyl dimethyl, and trialkyl methyl ammonium bromides.  |  Xi, Y., et al. 2007. J Colloid Interface Sci. 305: 150-8. PMID: 17045287
  3. Physicochemical investigation of a lipid with a new core structure for gene transfection: 2-amino-3-hexadecyloxy-2-(hexadecyloxymethyl)propan-1-ol.  |  Antipina, MN., et al. 2007. Langmuir. 23: 3919-26. PMID: 17309283
  4. An infrared study of adsorption of para-nitrophenol on mono-, di- and tri-alkyl surfactant intercalated organoclays.  |  Frost, RL., et al. 2008. Spectrochim Acta A Mol Biomol Spectrosc. 69: 239-44. PMID: 17481943
  5. Molecular restructuring of water and lipids upon the interaction of DNA with lipid monolayers.  |  Campen, RK., et al. 2010. J Am Chem Soc. 132: 8037-47. PMID: 20486664

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyltrioctadecylammonium bromide, 5 g

sc-235875
5 g
$107.00