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Methylmagnesium bromide (12% in Tetrahydrofuran, ca. 1mol/L) is a strong nucleophile used in organic synthesis. It functions as a source of the methyl anion, which can undergo nucleophilic addition reactions with a variety of electrophiles. Methylmagnesium bromide reacts with carbonyl compounds, such as ketones and aldehydes, to form alcohols through addition reactions. It can participate in Grignard reactions, where it adds to a variety of electrophiles, including alkyl halides, epoxides, and acid chlorides, to form new carbon-carbon bonds. Its mechanism of action involves the transfer of a methyl group to the electrophilic center of the substrate, leading to the formation of new carbon-carbon bonds and the generation of organic molecules with diverse structures.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methylmagnesium Bromide (12% in Tetrahydrofuran, ca. 1mol/L), 250 g | sc-295477 | 250 g | $147.00 | |||
US: Only available in the US |