Date published: 2026-3-15

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Methylhydrazine sulfate (CAS 302-15-8)

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CAS Number:
302-15-8
Molecular Weight:
144.15
Molecular Formula:
CH6N2•H2SO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methylhydrazine sulfate can be used as a reagent in organic reactions and has antimicrobial activity against bacteria. This compound is actually an isomeric mixture comprising two compounds, namely methylhydrazine and hydrazine sulphate. Moreover, it serves as a substituted hydrazine in the synthesis of pyrazole-3-carboxamide derivatives, particularly as 5-HT2B receptor antagonists.


Methylhydrazine sulfate (CAS 302-15-8) References

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  2. Synthesis of 3-phenylpyrazolo[4,3-b]pyridines via a convenient synthesis of 4-amino-3-arylpyrazoles and SAR of corticotropin-releasing factor receptor type-1 antagonists.  |  Wilcoxen, K., et al. 2003. Bioorg Med Chem Lett. 13: 3367-70. PMID: 12951127
  3. Effects of heterogeneous electron-transfer rate on the resolution of electrophoretic separations based on microfluidics with end-column electrochemical detection.  |  Wang, J., et al. 2009. Electrophoresis. 30: 3334-8. PMID: 19728304
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  5. Substrate oxidation by the heme edge of fungal peroxidases. Reaction of Coprinus macrorhizus peroxidase with hydrazines and sodium azide.  |  DePillis, GD. and Ortiz de Montellano, PR. 1989. Biochemistry. 28: 7947-52. PMID: 2611222
  6. 8-Azidoflavins as photoaffinity labels for flavoproteins.  |  Fitzpatrick, PF., et al. 1985. J Biol Chem. 260: 8483-91. PMID: 2861204
  7. Design, Synthesis, and Biological Evaluation of Pyrazoline-Based Hydroxamic Acid Derivatives as Aminopeptidase N (APN) Inhibitors.  |  Cao, J., et al. 2018. ChemMedChem. 13: 431-436. PMID: 29377564
  8. One-step synthesis of red/green dual-emissive carbon dots for ratiometric sensitive ONOO- probing and cell imaging.  |  Liu, J., et al. 2018. Nanoscale. 10: 13589-13598. PMID: 29978872
  9. Genotoxicity of a variety of hydrazine derivatives in the hepatocyte primary culture/DNA repair test using rat and mouse hepatocytes.  |  Mori, H., et al. 1988. Jpn J Cancer Res. 79: 204-11. PMID: 3130355
  10. Azobispyrazole Family as Photoswitches Combining (Near-) Quantitative Bidirectional Isomerization and Widely Tunable Thermal Half-Lives from Hours to Years*.  |  He, Y., et al. 2021. Angew Chem Int Ed Engl. 60: 16539-16546. PMID: 33852166
  11. Two-stage one-pot synthetic strategy for the key triazone-triazole intermediate of ensitrelvir (S-217622), an oral clinical candidate for treating COVID-19.  |  Hu, W., et al. 2022. RSC Adv. 12: 34808-34814. PMID: 36540243
  12. Structure and catalytic mechanism of horseradish peroxidase. Regiospecific meso alkylation of the prosthetic heme group by alkylhydrazines.  |  Ator, MA., et al. 1987. J Biol Chem. 262: 14954-60. PMID: 3667617
  13. Specific synthesis of 1-(5-glutamyl)-2-methylhydrazine by glutamine synthetase.  |  Rueppel, ML., et al. 1972. Biochemistry. 11: 2839-44. PMID: 4402868
  14. Hydrazine, methylhydrazine and methylhydrazine sulfate carcinogenesis in Swiss mice. Failure of ammonium hydroxide to interfere in the development of tumors.  |  Toth, B. 1972. Int J Cancer. 9: 109-18. PMID: 5015659
  15. Synthesis of pyridazine derivatives. 13. Synthesis of N1-(2-methyl-3-oxo-2,3-dihydro-4-pyridazinyl)-sulfanilamide derivatives.  |  Nakagome, T., et al. 1966. Chem Pharm Bull (Tokyo). 14: 1082-90. PMID: 5976938

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methylhydrazine sulfate, 5 g

sc-269599
5 g
$92.00