Molecular structure of Methyl vinyl sulfone, CAS Number: 3680-02-2
Methyl vinyl sulfone (CAS 3680-02-2)
Alternate Names:
(Methylsulfonyl)ethylene
CAS Number:
3680-02-2
Molecular Weight:
106.14
Molecular Formula:
C3H6O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Methyl vinyl sulfone is used in a Heck vinylation of aryl halides. It s a useful synthetic intermediate.Used as a derivatization reagent in an improved method for detection of pseudouridine in nucleoside mixtures by capillary HPLC-mass spectrometry. Additionally, it is used in the preparation of methylsulfonylethyl cellulose via Michael addition to cotton fabric.
Methyl vinyl sulfone (CAS 3680-02-2) References
- A novel one-pot reaction: zwitterionic rhodium complex-catalyzed hydroaminovinylation of vinyl sulfones and a vinylphosphonate. | Lin, YS., et al. 2001. J Am Chem Soc. 123: 7719-20. PMID: 11481003
- Population growth impairment of sulfur-containing compounds to Tetrahymena pyriformis. | Schultz, TW., et al. 2001. Environ Toxicol. 16: 543-9. PMID: 11769253
- Pseudouridine detection improvement by derivatization with methyl vinyl sulfone and capillary HPLC-mass spectrometry. | Emmerechts, G., et al. 2005. J Chromatogr B Analyt Technol Biomed Life Sci. 825: 233-8. PMID: 16029966
- Induction of NAD(P)H:quinone reductase in human peripheral blood lymphocytes. | Gordon, GB., et al. 1991. Carcinogenesis. 12: 2393-6. PMID: 1660793
- Mouse dominant lethal and bone marrow micronucleus studies on methyl vinyl sulfone and divinyl sulfone. | Shelby, MD., et al. 1991. Mutat Res. 250: 431-7. PMID: 1944356
- Development of novel peptidomimetics containing a vinyl sulfone moiety as proteasome inhibitors. | Ettari, R., et al. 2011. ChemMedChem. 6: 1228-37. PMID: 21506279
- O2-sulfonylethyl protected isopropylamine diazen-1-ium-1,2-diolates as nitroxyl (HNO) donors: synthesis, β-elimination fragmentation, HNO release, positive inotropic properties, and blood pressure lowering studies. | Huang, Z., et al. 2012. J Med Chem. 55: 10262-71. PMID: 23072318
- Vinyl Sulfone-Based Inhibitors of Nonstructural Protein 2 Block the Replication of Venezuelan Equine Encephalitis Virus. | Zhang, H., et al. 2020. ACS Med Chem Lett. 11: 2139-2145. PMID: 33214821
- A cascade reaction of cinnamyl azides with vinyl sulfones directly generates dihydro-pyrrolo-pyrazole heterocycles. | Carlson, AS., et al. 2021. Tetrahedron Lett. 67: PMID: 34054152
- Derivatives of methyl vinyl sulfone. Distribution and elimination of methyl (2,2-diphenyl)-vinyl sulfone labelled with 14carbon in mice. | Luu Duc, C., et al. 1978. Arzneimittelforschung. 28: 278-81. PMID: 580392
- Catalyzed double Michael addition of anilines to vinyl sulfone | Chen, J. J., Lu, C. V., & Brockman, R. N. 2003. Tetrahedron Letters. 44(17): 3459-3462.
- Vinyl sulfones as SEI-forming additives in propylene carbonate based electrolytes for lithium-ion batteries | R Wagner, S Brox, J Kasnatscheew, DR Gallus. 2014. Electrochemistry Communications. 40: 80-83.
- Reaction of Methyl Vinyl Sulfone with Schiff Bases Derived from α-Alanine Methyl Ester and Aromatic Aldehydes | Vasin, V. A., Kalyazin, V. A., Petrov, P. S., & Somov, N. V. 2019. Russian Journal of Organic Chemistry. 55: 426-435.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl vinyl sulfone, 5 g | sc-255301 | 5 g | $88.00 | |||
Methyl vinyl sulfone, 25 g | sc-255301A | 25 g | $368.00 |