Date published: 2026-4-24

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Methyl valerate (CAS 624-24-8)

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CAS Number:
624-24-8
Molecular Weight:
116.16
Molecular Formula:
CH3(CH2)3CO2CH3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl valerate, an organic compound with the molecular formula C6H12O2, has been extensively studied in scientific research, particularly in the fields of organic chemistry, flavor and fragrance development, and chemical synthesis. Research has focused on elucidating the mechanisms of methyl valerate synthesis and its diverse applications. Methyl valerate can be synthesized through the esterification of valeric acid with methanol, typically in the presence of an acid catalyst. Studies have explored the factors influencing the yield and selectivity of methyl valerate synthesis, such as reaction conditions, catalysts, and reaction kinetics. Furthermore, methyl valerate has been widely used as a flavoring and fragrance compound. Research has investigated its role in providing fruity and sweet notes, enhancing the sensory experience of various food products, beverages, and perfumes. Additionally, methyl valerate has been utilized as a starting material in the synthesis of specialty chemicals, such as plasticizers, solvents, and intermediates for pharmaceuticals. Its unique chemical properties and versatile reactivity have been harnessed to develop novel compounds with specific functionalities. The research applications of methyl valerate contribute to advancements in organic synthesis, flavor chemistry, and the development of functional compounds. By exploring the mechanisms and applications of methyl valerate, researchers aim to optimize its synthesis methods, discover new flavor and fragrance combinations, and explore its potential utilization in various industries.


Methyl valerate (CAS 624-24-8) References

  1. The Mammalian Olfactory Bulb Contributes to the Adaptation of Odor Responses: A Second Perceptual Computation Carried Out by the Bulb.  |  Storace, DA. and Cohen, LB. 2021. eNeuro. 8: PMID: 34380657
  2. Voltage imaging in the olfactory bulb using transgenic mouse lines expressing the genetically encoded voltage indicator ArcLight.  |  Platisa, J., et al. 2022. Sci Rep. 12: 1875. PMID: 35115567
  3. Methyl Internal Rotation in Fruit Esters: Chain-Length Effect Observed in the Microwave Spectrum of Methyl Hexanoate.  |  Dang, NN., et al. 2022. Molecules. 27: PMID: 35565991
  4. Benchmarking quantum chemical methods for accurate gas-phase structure predictions of carbonyl compounds: the case of ethyl butyrate.  |  Sutikdja, LW., et al. 2023. Phys Chem Chem Phys. 25: 7688-7696. PMID: 36857713
  5. Synergistic Effect of Diet and Physical Activity on a NAFLD Cohort: Metabolomics Profile and Clinical Variable Evaluation.  |  Calabrese, FM., et al. 2023. Nutrients. 15: PMID: 37299420
  6. Analysis of Volatile Esters and Alkanoic Acids by an Atmospheric Pressure Corona Discharge Ionization Collision-Induced Dissociation Mass Spectrometry in Positive-Ion Mode: Ionization, Fragmentation Patterns, and Discrimination between Isomeric Compounds.  |  Nishikido, Y. and Sekimoto, K. 2023. Mass Spectrom (Tokyo). 12: A0127. PMID: 37538446
  7. RIFM fragrance ingredient safety assessment, methyl valerate, CAS Registry Number 624-24-8.  |  Api, AM., et al. 2024. Food Chem Toxicol. 183 Suppl 1: 114398. PMID: 38134981
  8. Imaging different cell populations in the mouse olfactory bulb using the genetically encoded voltage indicator ArcLight.  |  Leong, LM. and Storace, DA. 2024. Neurophotonics. 11: 033402. PMID: 38288247
  9. Co-expression of metabolites and sensory attributes through weighted correlation network analysis to explore flavor-contributing factors in various Pyrus spp. Cultivars.  |  Zhang, W., et al. 2024. Food Chem X. 21: 101189. PMID: 38357376
  10. Characterization of Volatile Flavor Compounds and Aroma Active Components in Button Mushroom (Agaricus bisporus) across Various Cooking Methods.  |  Xie, L., et al. 2024. Foods. 13: PMID: 38472797

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl valerate, 1 ml

sc-215377
1 ml
$35.00