Date published: 2026-6-17

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Methyl Urocanate (CAS 52363-40-3)

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Alternate Names:
3-(1H-Imidazol-4-yl)-2-propenoic Acid Methyl Ester; Imidazole-4(or 5)-acrylic Acid Methyl Ester
CAS Number:
52363-40-3
Molecular Weight:
152.15
Molecular Formula:
C7H8N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl Urocanate functions as a UV filter in sunscreen formulations. It acts by absorbing UV radiation and converting it into less harmful forms of energy, thereby reducing the potential for DNA damage and skin aging caused by UV exposure. At the molecular level, Methyl Urocanate absorbs UVB radiation, which is known to cause sunburn and skin damage. Methyl Urocanate′s mechanism of action involves the conversion of UV radiation into heat, which dissipates harmlessly from the skin. This mechanism helps to protect the skin from the damaging effects of UV radiation, making Methyl Urocanate a useful component in sunscreen products for its ability to mitigate the harmful effects of sun exposure.


Methyl Urocanate (CAS 52363-40-3) References

  1. Lewis-acid catalysis of photochemical reactions. 6. Selective isomerization of .beta.-furylacrylic and urocanic esters.  |  Lewis, FD., et al. 1986. J Am Chem Soc. 108: 5964-8. PMID: 22175357
  2. Synthesis of [5,6]-Bicyclic Heterocycles with a Ring-Junction Nitrogen Atom: Rhodium(III)-Catalyzed C-H Functionalization of Alkenyl Azoles.  |  Halskov, KS., et al. 2017. Angew Chem Int Ed Engl. 56: 9183-9187. PMID: 28586164

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl Urocanate, 2 g

sc-211889
2 g
$632.00