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Methyl trichloroacetate (CAS 598-99-2)

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Alternate Names:
Trichloroacetic Acid Methyl Ester
Application:
Methyl trichloroacetate is a precursor of dichlorocarbene.
CAS Number:
598-99-2
Purity:
≥98%
Molecular Weight:
177.41
Molecular Formula:
C3H3Cl3O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl trichloroacetate is a precursor of dichlorocarbene.


Methyl trichloroacetate (CAS 598-99-2) References

  1. Methyl chloroacetate as an extraction solvent for coupling liquid-liquid semimicroextraction with micellar electrokinetic chromatography through on-capillary decomposition for the separation of neutral compounds with concentration enhancement.  |  Wang, T., et al. 2007. J Chromatogr A. 1147: 105-10. PMID: 17331520
  2. Tetramethylphosphinane as a new secondary phosphine synthon.  |  Nobbs, JD., et al. 2023. Commun Chem. 6: 85. PMID: 37120598
  3. Electrochemically Enabled Total Syntheses of Natural Products.  |  Hatch, CE. and Chain, WJ. 2023. ChemElectroChem. 10: PMID: 38106361
  4. Dialkyl Carbonate Synthesis Using Atmospheric Pressure of CO2.  |  Koizumi, H., et al. 2024. ACS Omega. 9: 25879-25886. PMID: 38911772
  5. Negative staining of proteins in polyacrylamide gels with methyl trichloroacetate.  |  Candiano, G., et al. 1996. Anal Biochem. 243: 245-8. PMID: 8954556
  6. Direct liquid-phase fluorination of methyl trichloroacetate and acetic anhydride.  |  Grakauskas, V. 1969. The Journal of Organic Chemistry. 34(4): 963-965.
  7. Reaction of methyl trichloroacetate with vinyltrimethylsilane in the presence of metal carbonyls  |  Kamyshova, A. A., & Chukovskaya, E. T. 1989. Bulletin of the Academy of Sciences of the USSR, Division of chemical science. 38: 2402-2404.
  8. Selective synthesis of α-chloroepoxides by electroreductive cross-coupling of methyl trichloroacetate with aliphatic aldehydes using reactive metal anodes  |  Nishiguchi, I., Goda, S., Kikkawa, T., Ishino, Y., & Maekawa, H. 2001. Journal of Electroanalytical Chemistry. 507(1-2): 185-190.
  9. Mannich‐Type Reaction Using Alkenyl Trichloroacetates Catalyzed by Dibutyltin Dimethoxide  |  Yanagisawa, A., Saito, H., Harada, M., & Arai, T. 2005. Advanced Synthesis & Catalysis. 347(11‐13): 1517-1522.
  10. Synthesis of Methyl Aziridine-2-Chloro-2-Carboxyletes through Electroreductive Cross Coupling of Methyl Trichloroacetate with Aromatic Imines  |  Nishiguchi, I., Kendrekar, P. S., & Maekawa, H. 2007. ECS Transactions. 6(7): 1.
  11. Electrosynthesis of cyclopropanes at the electrolysis of solutions of methyl esters of Di-and trichloroacetatic acids in aprotic media in the presence of acrylonitrile  |  Neverov, S. V., Sigacheva, V. L., & Petrosyan, V. A. 2011. Russian Journal of Electrochemistry. 47: 1134-1138.
  12. Methyl trihaloacetic esters as efficient and sustainable water suppressors in the synthesis of dimethyl carbonate from CO2  |  Marciniak, A. A., & Mota, C. J. 2017. ChemistrySelect. 2(5): 1808-1811.
  13. Synthesis of dimethyl carbonate from CO2 and methanol over CeO2: Role of copper as dopant and the use of methyl trichloroacetate as dehydrating agent  |  Marciniak, A. A., Alves, O. C., Appel, L. G., & Mota, C. J. 2019. Journal of catalysis. 371: 88-95.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl trichloroacetate, 25 g

sc-250385
25 g
$49.00