Molecular structure of Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate, CAS Number: 52373-72-5
Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate (CAS 52373-72-5)
Alternate Names:
(R)-(+)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid methyl ester; (+)-Methyl 2,3-O-Isopropylidene-D-glycerate
CAS Number:
52373-72-5
Molecular Weight:
160.17
Molecular Formula:
C7H12O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate, or MDMC, is a chiral molecule used as a chiral auxiliary in asymmetric synthesis. It has been employed in a variety of scientific research applications, including the synthesis of other compounds, the study of biochemical and physiological processes, and the development of new materials. For example, it has been used to study enzyme inhibition, protein folding, and cell signaling, as well as to develop polymers and nanomaterials. In addition, Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate may act to have anti-inflammatory and anti-cancer effects, as well as the ability to modulate cell signaling pathways.
Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate (CAS 52373-72-5) References
- Asymmetric synthesis of a 3-acyltetronic acid derivative, RK-682, and formation of its calcium salt during silica gel column chromatography. | Sodeoka, M., et al. 2001. Chem Pharm Bull (Tokyo). 49: 206-12. PMID: 11217111
- Simultaneous discrimination of diastereotopic groups and faces: the first example in intramolecular [3+2] and [2+2+1] cycloaddition reactions. | Ishikawa, T., et al. 2001. J Org Chem. 66: 3834-47. PMID: 11375005
- Optimization of a potent class of arylamide colony-stimulating factor-1 receptor inhibitors leading to anti-inflammatory clinical candidate 4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141). | Illig, CR., et al. 2011. J Med Chem. 54: 7860-83. PMID: 22039836
- Synthesis and determination of the enantiomeric purity of (R)- and (S)-2,3-Dihydroxy-3-methylbutyl p-Toluensulfonate† | and Dr. Eberhard Schrötter, Dr. Andre Hauser, Dr. Hans-Jürgen Hamann, Prof. Dr. sc. nat. Hans Schick, Dr. sc. nat. Bruno Schönecker. 1986. Journal für Praktische Chemie. Volume328, Issue5-6: Pages 705-712.
- Synthesis of methyl (±)-2,3-O-isopropylideneglycerate by electrochemical oxidation of (±)-1,2-O-isopropylideneglycerol | and Karl-Heinz Schwarz, Katharina Kleiner, Ralf Ludwig, Eberhard Schrötter, Hans Schick. Mai 1991. Liebigs Annalen der Chemie. Volume1991, Issue5 16.: Pages 503-504.
- Synthesis of (S)-1-(1H-indol-4-yloxy)-3-[4-(3-methoxyphenyl)-4-hydroxypiperidin-1-yl]-propan-2-ol (LY333068) succinate, and its 3-[14C]-isotopomer based on chiral glycerol-[14C] derivatives | and Boris A. Czeskis. June 1998. Journal of Labelled Compounds and Radiopharmaceuticals. Volume41, Issue6: Pages 465-475.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate, 1 g | sc-250324 | 1 g | $93.00 | |||
Methyl (R)-(+)-2,2-dimethyl-1,3-dioxolane-4-carboxylate, 25 g | sc-250324A | 25 g | $204.00 |