Date published: 2026-2-23

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Methyl-(PEG)4-NHS (CAS 622405-78-1)

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Alternate Names:
N-Succinimidyl 4,7,10,13-Tetraoxatetradecanoate; 4,7,10,13-Tetraoxatetradecanoic Acid N-Succinimidyl Ester
Application:
Methyl-(PEG)4-NHS is a versatile PEG-linker used to increase solubility
CAS Number:
622405-78-1
Molecular Weight:
333.33
Molecular Formula:
C14H23NO8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Methyl-(PEG)4-NHS is a versatile PEG-linker that binds to antibodies to reduce non-specific binding. Methyl-(PEG)4-NHS also binds to drugs and proteins to increase solubility, and to peptides to increase solubility and serum half-lifes. The spacer is 14 atoms and 15.6 Aring.


Methyl-(PEG)4-NHS (CAS 622405-78-1) References

  1. Electrical pulse fabrication of graphene nanopores in electrolyte solution.  |  Kuan, AT., et al. 2015. Appl Phys Lett. 106: 203109. PMID: 26045626
  2. Nonreciprocal and Conditional Cooperativity Directs the Pioneer Activity of Pluripotency Transcription Factors.  |  Li, S., et al. 2019. Cell Rep. 28: 2689-2703.e4. PMID: 31484078
  3. From deterministic to fuzzy decision-making in artificial cells.  |  Greiss, F., et al. 2020. Nat Commun. 11: 5648. PMID: 33159084
  4. TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA.  |  Kaur, P., et al. 2021. Nucleic Acids Res. 49: 13000-13018. PMID: 34883513
  5. Design, synthesis and biological activity evaluation of a series of bardoxolone methyl prodrugs.  |  Liu, L., et al. 2022. Bioorg Chem. 124: 105831. PMID: 35512420
  6. High-yield, ligation-free assembly of DNA constructs with nucleosome positioning sequence repeats for single molecule manipulation assays.  |  Lin, YY., et al. 2023. J Biol Chem. 104874. PMID: 37257819

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl-(PEG)4-NHS, 100 mg

sc-360251
100 mg
$208.00

Methyl-(PEG)4-NHS, 1 g

sc-360251A
1 g
$1040.00