Molecular structure of Methyl N,N,N′,N′-tetraisopropylphosphorodiamidite, CAS Number: 92611-10-4
Methyl N,N,N′,N′-tetraisopropylphosphorodiamidite (CAS 92611-10-4)
Alternate Names:
Bis(diisopropylamino)methoxyphosphine
CAS Number:
92611-10-4
Molecular Weight:
262.37
Molecular Formula:
[[(CH3)2CH]2N]2POCH3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Methyl N,N,N′,N′-tetraisopropylphosphorodiamidite plays a role in the creation of oligonucleotides, which are short sequences of DNA or RNA utilized extensively in various scientific research fields. Acting as a phosphoramidite compound, Methyl N,N,N′,N′-tetraisopropylphosphorodiamidite serves as the connecting link between nucleotides during the synthesis of oligonucleotides. By attaching itself to the 5′-hydroxyl group of one nucleotide, it reacts with the 3′-hydroxyl group of the following nucleotide in the sequence, thus initiating a repetitive process until the desired oligonucleotide is produced.
Methyl N,N,N′,N′-tetraisopropylphosphorodiamidite (CAS 92611-10-4) References
- 2-Methyl-5-tert-butylthiophenol--an odorless deprotecting reagent useful in synthesis of oligonucleotides and their analogs. | Kumar, RK., et al. 2003. Nucleosides Nucleotides Nucleic Acids. 22: 453-60. PMID: 12885125
- Synthesis of chemically stabilized phosmidosine analogues and the structure--activity relationship of phosmidosine. | Sekine, M., et al. 2004. J Org Chem. 69: 314-26. PMID: 14725442
- Chromophoric 5'-O-Silyl protection of N-protected 2'-ACE ribonucleosides for solid-phase RNA synthesis. | Delaney, MO., et al. 2008. Curr Protoc Nucleic Acid Chem. Chapter 2: Unit 2.14. PMID: 18428803
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl N,N,N′,N′-tetraisopropylphosphorodiamidite, 5 g | sc-235832 | 5 g | $153.00 |