Methyl (Methyl 3-Deoxy-D-arabino-heptulopyranosid)onate-7-Phosphate (CAS 91382-80-8)

Methyl (Methyl 3-Deoxy-D-arabino-heptulopyranosid)onate-7-phosphate is a carbohydrate derivative that mimics the natural compound 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP). This molecule is crucial in understanding carbohydrate metabolism, specifically in the shikimate pathway, which is responsible for the biosynthesis of aromatic amino acids in plants, fungi, and bacteria. The addition of methyl groups provides structural stability, allowing researchers to probe enzyme mechanisms involved in this pathway more precisely. In research, this compound is used to study DAHP synthase, the enzyme that catalyzes the first step in the shikimate pathway. By providing a stable and controlled substrate, it enables the detailed analysis of enzyme kinetics and the regulatory mechanisms governing DAHP synthase activity. It also serves as a precursor for synthesizing derivatives that are used in elucidating enzyme specificity and interactions within the pathway. The phosphate group at the C-7 position mimics the natural phosphate group present in DAHP, facilitating accurate studies of enzymatic reactions that involve phosphate transfer or binding. Overall, Methyl (Methyl 3-Deoxy-D-arabino-heptulopyranosid)onate-7-phosphate is instrumental in unraveling the molecular interactions and regulatory controls of the shikimate pathway, contributing significantly to carbohydrate biochemistry and metabolic engineering.