Date published: 2025-10-3

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Methyl linoleate (CAS 112-63-0)

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Alternate Names:
Linoleic acid methyl ester; Methyl cis,cis-9,12-octadecadienoate
CAS Number:
112-63-0
Purity:
≥94%
Molecular Weight:
294.47
Molecular Formula:
C19H34O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl linoleate, non-conjugated, is more easily oxidized than conjugated methyl linoleate. Methyl linoleate may be used as a model compound in oxidation/peroxidation assays to evaluate the anti-peroxidation activity of fullerenes, ellagitannins and other products. For instance, the oxidation of methyl linoleate in organic solution and phosphatidylcholine (PC) in liposomal membranes induced by an azo initiator has been used as a model for lipid peroxidation in vivo.


Methyl linoleate (CAS 112-63-0) References

  1. Catalytic epoxidation of a technical mixture of methyl oleate and methyl linoleate in ionic liquids using MoO(O2)2.2QOH (QOH = 8-quinilinol) as catalyst and NaHCO3 as co-catalyst.  |  Cai, SF., et al. 2009. Molecules. 14: 2935-46. PMID: 19701136
  2. Synthesis of linoleoyl ethanolamide.  |  Wang, X., et al. 2013. J Oleo Sci. 62: 427-33. PMID: 23728334
  3. Effect of droplet size on autoxidation rates of methyl linoleate and α-linolenate in an oil-in-water emulsion.  |  Ma, T., et al. 2013. J Oleo Sci. 62: 1003-8. PMID: 24292352
  4. Effects of Lobetyolin, Lobetyol and Methyl linoleate on Secretion, Production and Gene Expression of MUC5AC Mucin from Airway Epithelial Cells.  |  Yoon, YP., et al. 2014. Tuberc Respir Dis (Seoul). 77: 203-8. PMID: 25473407
  5. Alkylation of Methyl Linoleate with Propene in Ionic Liquids in the Presence of Metal Salts.  |  Pomelli, CS., et al. 2015. Molecules. 20: 21840-53. PMID: 26690107
  6. The Reaction of Thiyl Radical with Methyl Linoleate: Completing the Picture.  |  Chatgilialoglu, C., et al. 2017. J Am Chem Soc. 139: 4704-4714. PMID: 28253623
  7. Sageretia thea fruit extracts rich in methyl linoleate and methyl linolenate downregulate melanogenesis via the Akt/GSK3β signaling pathway.  |  Ko, GA., et al. 2018. Nutr Res Pract. 12: 3-12. PMID: 29399291
  8. Release kinetics of flavonoids in methyl linoleate from microparticles designed with inulin and channelizing agent.  |  Palma, M., et al. 2014. Food Res Int. 64: 99-105. PMID: 30011742
  9. Comparative studies on the effects of linoleate and methyl linoleate and their hydroperoxides on the respiration and reactivities of rat heart mitochondria.  |  Shiotani, A., et al. 1980. J Biochem. 88: 677-83. PMID: 6448251
  10. Effect of methyl linoleate administration on phospholipid fatty acid composition and osmotic fragility of erythrocytes in essential fatty acid deficient rats.  |  Huang, YS., et al. 1983. J Am Coll Nutr. 2: 55-61. PMID: 6886244
  11. Methyl hydroperoxy-epoxy-octadecenoate as an autoxidation product of methyl linoleate: a new inhibitor-uncoupler of mitochondrial respiration.  |  Imagawa, T., et al. 1982. J Biochem. 92: 1109-21. PMID: 7174640
  12. UV-initiated autoxidation of methyl linoleate in micelles studied by optical absorption.  |  Rekdal, K. and Melø, TB. 1995. Chem Phys Lipids. 75: 127-36. PMID: 7743563
  13. The reaction of low levels of nitrogen dioxide with methyl linoleate in the presence and absence of oxygen.  |  Gallon, AA. and Pryor, WA. 1994. Lipids. 29: 171-6. PMID: 8170286
  14. Reaction of alpha-tocopherol with alkyl and alkylperoxyl radicals of methyl linoleate.  |  Yamauchi, R., et al. 1993. Lipids. 28: 201-6. PMID: 8464351
  15. Reaction of alpha-tocopherol in heated bulk phase in the presence of methyl linoleate (13S)-hydroperoxide or methyl linoleate.  |  Yamauchi, R., et al. 1998. Lipids. 33: 77-85. PMID: 9470176

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl linoleate, 1 g

sc-215355
1 g
$56.00

Methyl linoleate, 5 g

sc-215355A
5 g
$112.00