Molecular structure of Methyl-L-NIO Ηydrochloride, CAS Number: 150403-96-6
Methyl-L-NIO Hydrochloride (CAS 150403-96-6)
Alternate Names:
N5-(1-iminopropyl)-L-ornithine, monohydrochloride
CAS Number:
150403-96-6
Molecular Weight:
223.70
Molecular Formula:
C8H17N3O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Methyl-L-NIO (hydrochloride) is a competitive NOS inhibitor that competes with L-arginine for the amino acid binding site. Methyl-L-NIO (hydrochloride) is a more potent inhibitor of NOS1 (nNOS) (Ki = 3.0 μM) than NOS3 (eNOS) (Ki = 10.0 μM) or NOS2 (iNOS) (Ki = 9.5 μM).
Methyl-L-NIO Hydrochloride (CAS 150403-96-6) References
- N5-(1-Imino-3-butenyl)-L-ornithine. A neuronal isoform selective mechanism-based inactivator of nitric oxide synthase. | Babu, BR. and Griffith, OW. 1998. J Biol Chem. 273: 8882-9. PMID: 9535869
Inhibitor of:
NOS1, NOS2, and NOS3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl-L-NIO Hydrochloride, 5 mg | sc-205389 | 5 mg | $66.00 | |||
Methyl-L-NIO Hydrochloride, 10 mg | sc-205389A | 10 mg | $126.00 |