Date published: 2025-10-15

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Methyl Glyoxylate (CAS 922-68-9)

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Alternate Names:
2-Oxo-acetic Acid Methyl Ester; Methyl Oxoacetate; Oxoacetic Acid Methyl Ester
Application:
Methyl Glyoxylate is a useful chemical for biological applications
CAS Number:
922-68-9
Purity:
≥85%
Molecular Weight:
88.06
Molecular Formula:
C3H4O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl Glyoxylate, also known as oxoacetic acid methyl ester, is a small molecule which represents the simplest example of an aldehydic ester that is possible. This compound could be useful as a synthetic reagent. Methyl glyoxylate (MG) is recognized for its ability to interact with diverse cellular constituents, such as proteins, lipids, and nucleic acids.


Methyl Glyoxylate (CAS 922-68-9) References

  1. Design, synthesis, and SAR of novel carbapenem antibiotics with high stability to Xanthomonas maltophilia oxyiminocephalosporinase type II.  |  Hakimelahi, GH., et al. 2000. J Med Chem. 43: 3632-40. PMID: 11020277
  2. Syntheses of (-)-funebrine and (-)-funebral, using sequential transesterification and intramolecular cycloaddition of a chiral nitrone.  |  Tamura, O., et al. 2004. J Org Chem. 69: 1475-80. PMID: 14986999
  3. Ab initio multireference study of Hetero-Diels-Alder reaction of buta-1,3-diene with alkyl glyoxylates.  |  Szefczyk, B., et al. 2008. J Mol Model. 14: 727-33. PMID: 18330601
  4. Integration of newly isolated biocatalyst and resin-based in situ product removal technique for the asymmetric synthesis of (R)-methyl mandelate.  |  Guo, JL., et al. 2010. Bioprocess Biosyst Eng. 33: 797-804. PMID: 20033429
  5. Synthetic and computational studies on the tricarboxylate core of 6,7-dideoxysqualestatin H5 involving a carbonyl ylide cycloaddition-rearrangement.  |  Hodgson, DM., et al. 2010. Org Biomol Chem. 8: 3975-84. PMID: 20601984
  6. Kinetics and products of gas-phase reactions of ozone with methyl methacrylate, methyl acrylate, and ethyl acrylate.  |  Bernard, F., et al. 2010. J Phys Chem A. 114: 8376-83. PMID: 20701345
  7. FTIR product distribution study of the Cl and OH initiated degradation of methyl acrylate at atmospheric pressure.  |  Blanco, MB., et al. 2010. Environ Sci Technol. 44: 7031-6. PMID: 20726521
  8. Total synthesis of cordatanine, structural reassignment of drymaritin, and anti-inflammatory activity of synthetic precursors.  |  Fang, HW., et al. 2015. Bioorg Med Chem Lett. 25: 3822-4. PMID: 26248804
  9. Alkylation of lithiated dimethyl tartrate acetonide with unactivated alkyl halides and application to an asymmetric synthesis of the 2,8-dioxabicyclo[3.2.1]octane core of squalestatins/zaragozic acids.  |  Sintim, HO., et al. 2019. Beilstein J Org Chem. 15: 1194-1202. PMID: 31293666
  10. Mechanisms and kinetic studies of OH-initiated atmospheric oxidation of methoxyphenols in the presence of O2 and NOx.  |  Sun, Y., et al. 2019. Phys Chem Chem Phys. 21: 21856-21866. PMID: 31553018

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl Glyoxylate, 5 g

sc-211881
5 g
$604.00

Methyl Glyoxylate, 25 g

sc-211881A
25 g
$2040.00

Methyl Glyoxylate, 100 g

sc-211881B
100 g
$6125.00