Date published: 2025-10-13

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Methyl glycolate (CAS 96-35-5)

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Alternate Names:
Methyl hydroxyacetate
CAS Number:
96-35-5
Purity:
98%
Molecular Weight:
90.08
Molecular Formula:
C3H603
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl glycolate is a compound that functions as a precursor in the synthesis of various organic compounds. It acts as a key building block in the production of esters, which are in the fragrance and flavor industries. Methyl glycolate undergoes esterification reactions with alcohols to form esters, contributing to the creation of a diverse range of aromatic and flavoring compounds. Its mode of action involves participating in chemical reactions that lead to the formation of esters, which are components in the development of various products. Plays a specific role in the molecular transformation process, facilitating the creation of esters through its reactivity with alcohols. In the development, methyl glycolate serves as a intermediate in the synthesis of esters, contributing to the production of diverse organic compounds.


Methyl glycolate (CAS 96-35-5) References

  1. Chiral recognition between alpha-hydroxylesters: a double-resonance IR/UV study of the complexes of methyl mandelate with methyl glycolate and methyl lactate.  |  Le Barbu-Debus, K., et al. 2008. J Phys Chem A. 112: 9731-41. PMID: 18778042
  2. Relationship between serum glycolate and falsely elevated lactate in severe ethylene glycol poisoning.  |  Manini, AF., et al. 2009. J Anal Toxicol. 33: 174-6. PMID: 19371468
  3. An efficient synthesis of the precursor of AI-2, the signalling molecule for inter-species quorum sensing.  |  Ascenso, OS., et al. 2011. Bioorg Med Chem. 19: 1236-41. PMID: 21216605
  4. An alternative synthetic approach for efficient catalytic conversion of syngas to ethanol.  |  Yue, H., et al. 2014. Acc Chem Res. 47: 1483-92. PMID: 24571103
  5. Surfactant-free nickel-silver core@shell nanoparticles in mesoporous SBA-15 for chemoselective hydrogenation of dimethyl oxalate.  |  Li, MM., et al. 2016. Chem Commun (Camb). 52: 2569-72. PMID: 26744750
  6. Chemocatalytic Conversion of Cellulosic Biomass to Methyl Glycolate, Ethylene Glycol, and Ethanol.  |  Xu, G., et al. 2017. ChemSusChem. 10: 1390-1394. PMID: 28266799
  7. Freezing copper as a noble metal-like catalyst for preliminary hydrogenation.  |  Sun, J., et al. 2018. Sci Adv. 4: eaau3275. PMID: 30588490
  8. Nanoporous Ni3P Evolutionarily Structured onto a Ni Foam for Highly Selective Hydrogenation of Dimethyl Oxalate to Methyl Glycolate.  |  Zhu, J., et al. 2019. ACS Appl Mater Interfaces. 11: 37635-37643. PMID: 31538477
  9. Intercalating lithium into the lattice of silver nanoparticles boosts catalytic hydrogenation of carbon-oxygen bonds.  |  Duan, XP., et al. 2021. Chem Sci. 12: 8791-8802. PMID: 34257879
  10. Synthesis of methyl glycolate by hydrogenation of dimethyl oxalate with a P modified Co/SiO2 catalyst.  |  Zhuang, Z., et al. 2022. Chem Commun (Camb). 58: 1958-1961. PMID: 35043789
  11. Ni-Modified Ag/SiO2 Catalysts for Selective Hydrogenation of Dimethyl Oxalate to Methyl Glycolate.  |  Cheng, S., et al. 2022. Nanomaterials (Basel). 12: PMID: 35159752
  12. Highly selective hydrogenation of dimethyl oxalate to methyl glycolate and ethylene glycol over an amino-assisted Ru-based catalyst.  |  Song, L., et al. 2022. Chem Commun (Camb). 58: 11657-11660. PMID: 36164825
  13. Poly(Butylene Adipate/Terephthalate-Co-Glycolate) Copolyester Synthesis Based on Methyl Glycolate with Improved Barrier Properties: From Synthesis to Structure-Property.  |  Wang, Y., et al. 2022. Int J Mol Sci. 23: PMID: 36232379
  14. Selective Hydrogenation of Dimethyl Oxalate to Methyl Glycolate over Boron-Modified Ag/SiO2 Catalysts.  |  Cheng, S., et al. 2022. ACS Omega. 7: 41224-41235. PMID: 36406499
  15. Conversion of glucose to methyl glycolate in subcritical methanol.  |  Weng, Y., et al. 2023. Chem Commun (Camb). 59: 4340-4343. PMID: 36945862

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl glycolate, 5 g

sc-250372
5 g
$32.00