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Methyl γ-Linolenate is one of polyunsaturated fatty acids (PUFAs) that are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet. Methyl γ-Linolenate (Methyl GLA) is an esterified version of the free acid which is less water soluble. GLA is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak leukotriene B4 (LTB4) receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 muM. Methyl γ-Linolenate produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl γ-Linolenate, 50 mg | sc-205388 | 50 mg | $40.00 | |||
Methyl γ-Linolenate, 100 mg | sc-205388A | 100 mg | $71.00 |