Date published: 2025-9-19

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Methyl γ-Linolenate (CAS 16326-32-2)

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Alternate Names:
γ-Linolenic Acid methyl ester
Application:
Methyl γ-Linolenate is a leukotriene B4 (LTB4) receptor antagonist
CAS Number:
16326-32-2
Purity:
>98%
Molecular Weight:
292.46
Molecular Formula:
C19H32O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl γ-Linolenate is one of polyunsaturated fatty acids (PUFAs) that are essential nutrients that show distinct deficiency syndromes when not present in adequate amounts in the diet. Methyl γ-Linolenate (Methyl GLA) is an esterified version of the free acid which is less water soluble. GLA is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak leukotriene B4 (LTB4) receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 muM. Methyl γ-Linolenate produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.


Methyl γ-Linolenate (CAS 16326-32-2) References

  1. Effects of the electrical conductivity of a soilless culture system on gamma linolenic acid levels in borage seed oil.  |  Urrestarazu, M., et al. 2019. PLoS One. 14: e0207106. PMID: 30779750
  2. New observations on the effect of camellia oil on fatty liver disease in rats.  |  Li, CX. and Shen, LR. J Zhejiang Univ Sci B. 21: 657-667. PMID: 32748581
  3. Antioxidant Activity of Hemp (Cannabis sativa L.) Seed Oil in Drosophila melanogaster Larvae under Non-Stress and H2O2-Induced Oxidative Stress Conditions.  |  Vitorović, J., et al. 2021. Antioxidants (Basel). 10: PMID: 34067432
  4. Insight into the Secondary Metabolites of Geum urbanum L. and Geum rivale L. Seeds (Rosaceae).  |  Bunse, M., et al. 2021. Plants (Basel). 10: PMID: 34203945
  5. Hepatoprotective and Anti-Obesity Properties of Sardine By-Product Oil in Rats Fed a High-Fat Diet.  |  Daidj, NBB. and Lamri-Senhadji, M. 2021. Prev Nutr Food Sci. 26: 285-295. PMID: 34737989
  6. Identifying volatile and non-volatile organic compounds to discriminate cultivar, growth location, and stage of ripening in olive fruits and oils.  |  Greco, M., et al. 2022. J Sci Food Agric. 102: 4500-4513. PMID: 35122271
  7. Evening Primrose Oil Enhances Tamoxifen's Anticancer Activity against Breast Cancer Cells by Inducing Apoptosis, Inhibiting Angiogenesis, and Arresting the Cell Cycle.  |  Abd-Alhaseeb, MM., et al. 2022. Molecules. 27: PMID: 35458590
  8. The Dynamic Change in Fatty Acids during the Postharvest Process of Oolong Tea Production.  |  Zhou, ZW., et al. 2022. Molecules. 27: PMID: 35807544
  9. Formulation and Characterization of O/W Nanoemulsions of Hemp Seed Oil for Protection from Steatohepatitis: Analysis of Hepatic Free Fatty Acids and Oxidation Markers.  |  Qushawy, M., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 35890162
  10. Pharmacokinetic and metabolomic studies with a BIO 300 Oral Powder formulation in nonhuman primates.  |  Li, Y., et al. 2022. Sci Rep. 12: 13475. PMID: 35931769
  11. Utility of fatty acid profile and in vitro immune cell activation for chemical and biological standardization of Arthrospira/Limnospira.  |  Huh, J., et al. 2022. Sci Rep. 12: 15657. PMID: 36123360
  12. Increased LC PUFA Levels in the Serum of Pregnant Women and Their Children as a Result of Dietary Supplementation with 'Omega' Fatty Acids.  |  Broś-Konopielko, M., et al. 2023. Nutrients. 15: PMID: 36615888
  13. [Determination of 39 fatty acids in liver of rats by gas chromatography-mass spectrometry].  |  Wu, YX., et al. 2023. Se Pu. 41: 443-449. PMID: 37087610

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl γ-Linolenate, 50 mg

sc-205388
50 mg
$40.00

Methyl γ-Linolenate, 100 mg

sc-205388A
100 mg
$71.00